You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Discontinued ProductGlimepiride (Cat. No. 2396) has been withdrawn from sale for commercial reasons.
Biological Activity for Glimepiride
Glimepiride is a potent Kir6 (KATP) channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac Kir6 channels with an IC50 of 6.8 nM.
Technical Data for Glimepiride
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for Glimepiride
References are publications that support the biological activity of the product.
Lawrence et al (2002) Effect of metabolic inhibition on glimep. block of native and cloned cardiac sacrolemmal KATP channels. Br.J.Pharmacol. 136 746 PMID: 12086984
View Related Products by Product Action
Keywords: Glimepiride, Glimepiride supplier, KATP, channels, openers, Potassium, KIR, Inward, Rectifier, K+, Kir6, Amaryl, Glimperide, rectifier, Channels, 2396, Tocris Bioscience
Citations for Glimepiride
Citations are publications that use Tocris products.
Currently there are no citations for Glimepiride.
Reviews for Glimepiride
Average Rating: 5 (Based on 1 Review.)
Have you used Glimepiride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
In pancreatic beta cells,ATP dependent potassium channels regulate glucose-dependent insulin secretion and serve as the target for sulfonylurea drugs used to treat type 2 diabetes.To understand the role of BK channels on insulin secretion,Glimepiride was used.