You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
TRPC5 inhibitor. Inhibits Ca2+ entry into TRPC5 expressing cells. Inhibits LPS-induced expression of TNFα, IL-6, IL-1β, COX2 and iNOS, in vitro. Attenuates microglial activation, loss of dopaminergic neurons and motor dysfunction in a LPS-induced rat model of Parkinson's disease. Also inhibits proliferation in breast cancer cell lines. Induces autophagy.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 270.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.7 mL||18.5 mL||37 mL|
|5 mM||0.74 mL||3.7 mL||7.4 mL|
|10 mM||0.37 mL||1.85 mL||3.7 mL|
|50 mM||0.07 mL||0.37 mL||0.74 mL|
References are publications that support the biological activity of the product.
Naylor et al (2016) Natural and synthetic flavonoid modulation of TRPC5 channels. Br.J.Pharmacol. 173 562 PMID: 26565375
Chen et al (2017) Galangin reduces the loss of DArgic neurons in an LPS-evoked model of Parkinson's disease in rats. Int.J.Mol.Sci. 19 PMID: 29267220
So et al (1996) Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices. Nutr.Cancer. 26 167 PMID: 8875554
Wen et al (2012) Galangin induces autophagy through upregulation of p53 in HepG2 cells. Pharmacology. 89 247 PMID: 22507894
If you know of a relevant reference for Galangin, please let us know.
View Related Products by Product Action
Keywords: Galangin, Galangin supplier, Galangin, TRPC5, inhibitors, autophagy, inducers, flavonoids, inhibits, induces, Autophagy, TRPC, 6494, Tocris Bioscience
Citations for Galangin
Citations are publications that use Tocris products.
Currently there are no citations for Galangin. Do you know of a great paper that uses Galangin from Tocris? Please let us know.
Reviews for Galangin
There are currently no reviews for this product. Be the first to review Galangin and earn rewards!
Have you used Galangin?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells