Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewFK 409
Description: NO donor
Alternative Names: NOR-3, (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
Chemical Name: (2E,3E)-4-Ethyl-2-(hydroxyimino)-5-nitro-3-hexenamide
Purity: ≥98% (HPLC)
Biological Activity for FK 409
NO donor; exhibits vasorelaxant (EC50 = 3.9 nM) and antiplatelet activities (IC50 = 4.9 μM). Cell permeable.
Technical Data for FK 409
| M. Wt | 215.21 |
| Formula | C8H13N3O4 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 138472-01-2 |
| PubChem ID | 6437875 |
| InChI Key | MZAGXDHQGXUDDX-AGLLBGTNSA-N |
| Smiles | CC(/C(CC)=C/C(C(N)=O)=N\O)[N+]([O-])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for FK 409
References for FK 409
References are publications that support the biological activity of the product.
Fukuyama et al (1997) Structure-activity relationships of spontaneous nitric oxide releasers, FK409 and its derivatives. J.Pharmacol.Exp.Ther. 282 236 PMID: 9223559
View Related Products by Target
Keywords: FK 409, FK 409 supplier, FK409, NO, donors, nitric, oxide, vasorelaxant, cell, permeable, NOR-3, (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide, Donors, /, Precursors, ROS, 3105, Tocris Bioscience
1 Citation for FK 409
Citations are publications that use Tocris products. Selected citations for FK 409 include:
Cortés-Montero et al (2019) The axonal motor neuropathy-related HINT1 protein is a zinc- and calmodulin-regulated cysteine SUMO protease. Antioxid Redox Signal PMID: 31088288
Reviews for FK 409
There are currently no reviews for this product. Be the first to review FK 409 and earn rewards!
Have you used FK 409?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Research Product Guide
A collection of over 750 products for cancer research, the guide includes research tools for the study of:
- Cancer Metabolism
- Epigenetics in Cancer
- Receptor Signaling
- Cell Cycle and DNA Damage Repair
- Angiogenesis
- Invasion and Metastasis