NO donor; exhibits vasorelaxant (EC50 = 3.9 nM) and antiplatelet activities (IC50 = 4.9 μM). Cell permeable.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 215.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.65 mL||23.23 mL||46.47 mL|
|5 mM||0.93 mL||4.65 mL||9.29 mL|
|10 mM||0.46 mL||2.32 mL||4.65 mL|
|50 mM||0.09 mL||0.46 mL||0.93 mL|
References are publications that support the products' biological activity.
Fukuyama et al (1997) Structure-activity relationships of spontaneous nitric oxide releasers, FK409 and its derivatives. J.Pharmacol.Exp.Ther. 282 236 PMID: 9223559
If you know of a relevant reference for FK 409, please let us know.
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Keywords: FK 409, supplier, FK409, NO, donors, nitric, oxide, vasorelaxant, cell, permeable, NOR-3, (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide, NO, Donors, /, Precursors, ROS, Donors, NO, Donors, /, Precursors, Tocris Bioscience
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