Nitric oxide donor. Activates an inward current in cultured rat cerebellar granules cells. Increases cGMP production in cultured vascular smooth muscle cells. Reduces contractility of cardiac muscle preparations in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 163.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||6.13 mL||30.64 mL||61.28 mL|
|5 mM||1.23 mL||6.13 mL||12.26 mL|
|10 mM||0.61 mL||3.06 mL||6.13 mL|
|50 mM||0.12 mL||0.61 mL||1.23 mL|
References are publications that support the biological activity of the product.
Thompson et al (2009) The NO donor DETA-NONOate reversibly activates an inward current in neurones and is not mediated by the released nitric oxide. Br.J.Pharmacol. 158 1338 PMID: 19785659
Olson et al (1997) Selective guanylyl cyclase inhibitor reverses nitric oxide-induced vasorelaxation. Hypertension 29 254 PMID: 9039111
Wegener et al (2002) Effects of nitric oxide donors on cardiac contractility in wild-type and myoglobin-deficient mice. Br.J.Pharmacol. 136 415 PMID: 12023944
If you know of a relevant reference for DETA NONOate, please let us know.
View Related Products by Target
Keywords: DETA NONOate, DETA NONOate supplier, nitric, oxide, releasing, compounds, donors, NO, Donors, /, Precursors, ROS, 6077, Tocris Bioscience
Citations for DETA NONOate
Citations are publications that use Tocris products.
Currently there are no citations for DETA NONOate. Do you know of a great paper that uses DETA NONOate from Tocris? Please let us know.
Reviews for DETA NONOate
There are currently no reviews for this product. Be the first to review DETA NONOate and earn rewards!
Have you used DETA NONOate?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.