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Cat.No. 0659 - FGIN-1-43 | C28H36Cl2N2O | CAS No. 145040-29-5
Description: Potent, specific ligand for mitochondrial DBI receptor
Chemical Name: N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide
Purity: ≥98%
Literature (2)

Biological Activity

Most active of the 2-aryl-3-indoleacetamides; a new class of potent and specific ligands as probes for the mitochondial DBI receptor (peripheral benzodiazepine receptor).

Technical Data

M. Wt 487.51
Formula C28H36Cl2N2O
Storage Store at RT
Purity ≥98%
CAS Number 145040-29-5
PubChem ID 3995234

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 24.37 50

Preparing Stock Solutions

The following data is based on the product molecular weight 487.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.1 mL 20.51 mL 41.02 mL
2.5 mM 0.82 mL 4.1 mL 8.2 mL
5 mM 0.41 mL 2.05 mL 4.1 mL
25 mM 0.08 mL 0.41 mL 0.82 mL

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References are publications that support the biological activity of the product.

Kozikowski et al (1993) Chemistry, binding affinities, and behavioural properties of a new class of "antineophobic" mitochondrial DBI receptor (mDRC) ligands. J.Med.Chem. 36 2908 PMID: 8411007

Romeo et al (1992) 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J.Pharmacol.Exp.Ther. 262 971 PMID: 1326631

If you know of a relevant reference for FGIN-1-43, please let us know.

Keywords: FGIN-1-43, FGIN-1-43 supplier, Potent, specific, ligand, mitochondrial, DBI, receptor, GABAA, Receptors, FGIN143, Translocator, Protein, 0659, Tocris Bioscience

Citations for FGIN-1-43

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