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Most active of the 2-aryl-3-indoleacetamides; a new class of potent and specific ligands as probes for the mitochondial DBI receptor (peripheral benzodiazepine receptor).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 487.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.1 mL||20.51 mL||41.02 mL|
|2.5 mM||0.82 mL||4.1 mL||8.2 mL|
|5 mM||0.41 mL||2.05 mL||4.1 mL|
|25 mM||0.08 mL||0.41 mL||0.82 mL|
References are publications that support the biological activity of the product.
Kozikowski et al (1993) Chemistry, binding affinities, and behavioural properties of a new class of "antineophobic" mitochondrial DBI receptor (mDRC) ligands. J.Med.Chem. 36 2908 PMID: 8411007
Romeo et al (1992) 2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J.Pharmacol.Exp.Ther. 262 971 PMID: 1326631
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Keywords: FGIN-1-43, FGIN-1-43 supplier, Potent, specific, ligand, mitochondrial, DBI, receptor, GABAA, Receptors, FGIN143, Translocator, Protein, 0659, Tocris Bioscience
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Literature in this Area
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