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Cat.No. 3970 - Ercalcitriol | C28H44O3 | CAS No. 60133-18-8
Description: Active metabolite of vitamin D2
Alternative Names: 1α,25-Dihydroxyvitamin D2
Chemical Name: (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7α-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
Purity: ≥95% (HPLC)
Citations (1)

Biological Activity

Active metabolite of vitamin D2. Exhibits equipotent antirachitic activity in rats as calcitriol (Cat. No. 2551).

Technical Data

M. Wt 428.65
Formula C28H44O3
Storage Desiccate at -20°C
Purity ≥95% (HPLC)
CAS Number 60133-18-8
PubChem ID 9547243
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](/C=C/[C@H](C)C(C)(O)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
ethanol 2.14 5

Preparing Stock Solutions

The following data is based on the product molecular weight 428.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 46.66 mL 233.29 mL 466.58 mL
0.25 mM 9.33 mL 46.66 mL 93.32 mL
0.5 mM 4.67 mL 23.33 mL 46.66 mL
2.5 mM 0.93 mL 4.67 mL 9.33 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the biological activity of the product.

Rambeck et al (1984) Biological activity of 1 alpha,25-dihydroxyergocalciferol in rachitic chicks and in rats. Int.J.Vitamin.Nutr.Res. 54 135

If you know of a relevant reference for Ercalcitriol, please let us know.

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Keywords: Ercalcitriol, Ercalcitriol supplier, Vitamin, D, receptor, VDR, agonists, Receptors, VDR-like, 1a,25-DihydroxyvitaminD2, 1alpha,25-DihydroxyvitaminD2, 1α,25-DihydroxyvitaminD2, 1a,25-Dihydroxyvitamin, D2, 3970, Tocris Bioscience

1 Citation for Ercalcitriol

Citations are publications that use Tocris products. Selected citations for Ercalcitriol include:

Kim et al (2014) Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells. Sci Rep 77 73 PMID: 25237378

Do you know of a great paper that uses Ercalcitriol from Tocris? Please let us know.

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