Glycoprotein (GP) IIb/IIIa inhibitor. Reversibly and competitively binds to GPIIa/IIIb on platelets, inhibiting aggregation.
(Modifications: X1 = Mpa, X2 = Har, Disulfide bridge: 1-7, Cys-7 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 5 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 832.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.2 mL||6.01 mL||12.01 mL|
|5 mM||0.24 mL||1.2 mL||2.4 mL|
|10 mM||0.12 mL||0.6 mL||1.2 mL|
|50 mM||0.02 mL||0.12 mL||0.24 mL|
References are publications that support the products' biological activity.
O'Shea and Tcheng (2002) Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa. Expert Opin.Pharmacother. 3 1199 PMID: 12150697
If you know of a relevant reference for Eptifibatide, please let us know.
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Keywords: Eptifibatide, supplier, Glycoprotein, GP, IIb/IIIa, inhibitors, inhibits, platelets, aggregation, antiplatelet, Integrins, Cell, Adhesion, Molecules, Integrins, Tocris Bioscience
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