Discontinued Product

Eptifibatide (Cat. No. 4725) has been withdrawn from sale for commercial reasons.
Description: Glycoprotein IIb/IIIa inhibitor; inhibits platelet aggregation
Purity: ≥95% (HPLC)
Literature (2)

Biological Activity for Eptifibatide

Eptifibatide is a glycoprotein (GP) IIb/IIIa inhibitor. Reversibly and competitively binds to GPIIa/IIIb on platelets, inhibiting aggregation.

Technical Data for Eptifibatide

M. Wt 832.5
Formula C35H49N11O9S2
Sequence XXGDWPC

(Modifications: X1 = Mpa, X2 = Har, Disulfide bridge: 1-7, Cys-7 = C-terminal amide)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 188627-80-7
PubChem ID 448812
Smiles NC(=N)NCCCC[C@@H]1NC(=O)CCSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Eptifibatide

Certificate of Analysis / Product Datasheet
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References for Eptifibatide

References are publications that support the biological activity of the product.

O'Shea and Tcheng (2002) Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa. Expert Opin.Pharmacother. 3 1199 PMID: 12150697

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Keywords: Eptifibatide, Eptifibatide supplier, Glycoprotein, GP, IIb/IIIa, inhibitors, inhibits, platelets, aggregation, antiplatelet, Integrins, Cell, Adhesion, Molecules, 4725, Tocris Bioscience

Citations for Eptifibatide

Citations are publications that use Tocris products.

Currently there are no citations for Eptifibatide.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Angiogenesis in Cancer Poster

Angiogenesis in Cancer Poster

This poster summarizes the pathogenesis of angiogenesis in cancer, as well as some of the main angiogenesis therapeutic targets.

Enabling Research By Provision of Chemical Tools Poster

Enabling Research By Provision of Chemical Tools Poster

The Tocris chemistry team has considerable chemistry knowledge and skill which it has recently been applying to the generation of new chemical probes from known tools and compounds to help answer biological questions. This poster presents some of the work carried out by Tocris scientists and focuses on two areas: the generation of libraries of chemical building blocks to support Degrader (PROTAC) research and the development of a fluorescent probe to study integrin biology. Presented at Chemical Tools for Complex Biological Systems II, 2019, Janelia Research Campus, USA.