Eptifibatide

Pricing Availability Delivery Time Qty
Cat.No. 4725 - Eptifibatide | Mpa-Har-Gly-Asp-Trp-Pro-Cys-NH2 | CAS No. 188627-80-7
Description: Glycoprotein IIb/IIIa inhibitor; inhibits platelet aggregation
Datasheet
Citations
Literature

Biological Activity

Glycoprotein (GP) IIb/IIIa inhibitor. Reversibly and competitively binds to GPIIa/IIIb on platelets, inhibiting aggregation.

Technical Data

M. Wt 832.5
Formula C35H49N11O9S2
Sequence XXGDWPC-NH2

(Modifications: X1 = Mpa, X2 = Har, Disulfide bridge: 1-7, Cys-7 = C-terminal amide)

Storage Store at -20°C
CAS Number 188627-80-7
PubChem ID 448812
InChI Key CZKPOZZJODAYPZ-LROMGURASA-N
Smiles NC(=N)NCCCC[C@@H]1NC(=O)CCSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 5 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 832.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.2 mL 6.01 mL 12.01 mL
5 mM 0.24 mL 1.2 mL 2.4 mL
10 mM 0.12 mL 0.6 mL 1.2 mL
50 mM 0.02 mL 0.12 mL 0.24 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

O'Shea and Tcheng (2002) Eptifibatide: a potent inhibitor of the platelet receptor integrin glycoprotein IIb/IIIa. Expert Opin.Pharmacother. 3 1199 PMID: 12150697


If you know of a relevant reference for Eptifibatide, please let us know.

View Related Products by Product Action

View all Integrin Inhibitors

Keywords: Eptifibatide, supplier, Glycoprotein, GP, IIb/IIIa, inhibitors, inhibits, platelets, aggregation, antiplatelet, Integrins, Cell, Adhesion, Molecules, Integrins, Tocris Bioscience

Citations for Eptifibatide

Citations are publications that use Tocris products.

Currently there are no citations for Eptifibatide. Do you know of a great paper that uses Eptifibatide from Tocris? If so please let us know.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

Immunology

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation

Pathways for Eptifibatide

Protocols

TODO: Add Protocols