Elinogrel

Pricing Availability Delivery Time Qty
Cat.No. 5316 - Elinogrel | C20H15ClFN5O5S2 | CAS No. 936500-94-6
Description: P2Y12 antagonist
Chemical Name: 5-Chloro-N-[[[4-[6-Fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

P2Y12 antagonist; exhibits antiplatelet activity.

Compound Libraries

Elinogrel is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 523.95
Formula C20H15ClFN5O5S2
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 936500-94-6
PubChem ID 16066663
InChI Key LGSDFTPAICUONK-UHFFFAOYSA-N
Smiles O=C(NS(C4=CC=C(Cl)S4)(=O)=O)NC(C=C3)=CC=C3N2C(C1=CC(F)=C(NC)C=C1NC2=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 52.4 100

Preparing Stock Solutions

The following data is based on the product molecular weight 523.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.91 mL 9.54 mL 19.09 mL
5 mM 0.38 mL 1.91 mL 3.82 mL
10 mM 0.19 mL 0.95 mL 1.91 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Cattaneo et al (2010) State of the art of new P2Y12 antagonists. Intern.Emerg.Med. 5 385 PMID: 20177818


If you know of a relevant reference for Elinogrel, please let us know.

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Keywords: P2Y12 antagonists antiplatelet Purinergic P2Y Receptors

Citations for Elinogrel

Citations are publications that use Tocris products.

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Literature in this Area

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P2X and P2Y Receptors

P2X and P2Y Receptors Scientific Review

Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.

Cardiovascular

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Pathways for Elinogrel

Protocols

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