DMeOB

Discontinued Product

DMeOB (Cat. No. 1953) has been withdrawn from sale for commercial reasons.
Cat.No. 1953 - DMeOB | C16H16N2O2 | CAS No. 40252-74-2
Description: Negative allosteric modulator of mGlu5 receptors
Chemical Name: [(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (10)

Biological Activity

Negative allosteric modulator of the metabotropic glutamate receptor mGlu5; displays reversible non-competitive inhibition of mGlu5-mediated responses (IC50 = 3 μM).

Technical Data

M. Wt 268.31
Formula C16H16N2O2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 40252-74-2
PubChem ID 9604993
InChI Key CWHVUMNEZIBZFC-UHFFFAOYSA-N
Smiles COC1=CC(=CC=C1)\N=C\N=C\C1=CC(OC)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

O'Brien et al (2003) A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5 Mol.Pharmacol. 64 731 PMID: 12920211

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Keywords: DMeOB, DMeOB supplier, Negative, allosteric, modulators, mGlu5, mGluR5, Group, I, Receptors, Glutamate, Metabotropic, nams, (Metabotropic), 1953, Tocris Bioscience

Citations for DMeOB

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