(±)-MDMA hydrochloride

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Cat.No. 3027 - (±)-MDMA hydrochloride | C11H15NO2.HCl | CAS No. 92279-84-0
Description: Inhibitor of 5-HT and dopamine uptake; hallucinogenic
Alternative Names: Methylenedioxymethamphetamine hydrochloride
Chemical Name: N,α,-Dimethyl-3,4-methylenedioxyphenethylamine hydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Hallucinogenic compound that inhibits 5-HT and dopamine uptake.

Technical Data

M. Wt 229.7
Formula C11H15NO2.HCl
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 92279-84-0
PubChem ID 71285
InChI Key LUWHVONVCYWRMZ-UHFFFAOYSA-N
Smiles CC(NC)CC1=CC(OCO2)=C2C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 22.97 100

Preparing Stock Solutions

The following data is based on the product molecular weight 229.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.35 mL 21.77 mL 43.54 mL
5 mM 0.87 mL 4.35 mL 8.71 mL
10 mM 0.44 mL 2.18 mL 4.35 mL
50 mM 0.09 mL 0.44 mL 0.87 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Iravani et al (2000) Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulata, and the dorsal raphe nucleus slices. Synapse 36 275 PMID: 10819905

Fleckenstein et al (2007) New insights into the mechanism of action of amphetamines. Annu.Rev.Pharmacol.Toxicol. 47 681 PMID: 17209801

Boyle et al (2007) MDMA ("ecstasy") suppresses the innate IFN-γ response in vivo: a critical role for the anti-inflammatory cytokine IL-10. Eur.J.Pharmacol. 572 228 PMID: 17689526


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Citations for (±)-MDMA hydrochloride

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5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Pathways for (±)-MDMA hydrochloride

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