(±)-MDMA hydrochloride

Discontinued Product

(±)-MDMA hydrochloride (Cat. No. 3027) has been withdrawn from sale for commercial reasons.
Description: Inhibitor of 5-HT and dopamine uptake; hallucinogenic
Alternative Names: Methylenedioxymethamphetamine hydrochloride
Chemical Name: ±-N,α,-Dimethyl-3,4-methylenedioxyphenethylamine hydrochloride
Purity: ≥98% (HPLC)
Reviews (1)
Literature (1)

Biological Activity for (±)-MDMA hydrochloride

(±)-MDMA hydrochloride is a hallucinogenic compound that inhibits 5-HT and dopamine uptake.

Technical Data for (±)-MDMA hydrochloride

M. Wt 229.7
Formula C11H15NO2.HCl
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 64057-70-1
PubChem ID 71285
Smiles CC(NC)CC1=CC(OCO2)=C2C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (±)-MDMA hydrochloride

Certificate of Analysis / Product Datasheet
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References for (±)-MDMA hydrochloride

References are publications that support the biological activity of the product.

Iravani et al (2000) Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or DA release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulata, and the dorsal raphe nucleus slices. Synapse 36 275 PMID: 10819905

Fleckenstein et al (2007) New insights into the mechanism of action of amphetamines. Annu.Rev.Pharmacol.Toxicol. 47 681 PMID: 17209801

Boyle et al (2007) MDMA ("ecstasy") suppresses the innate IFN-γ response in vivo: a critical role for the anti-inflammatory cytokine IL-10. Eur.J.Pharmacol. 572 228 PMID: 17689526

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Keywords: (±)-MDMA hydrochloride, (±)-MDMA hydrochloride supplier, inhibitors, inhibits, 5-HT, dopamine, reuptake, hallucinogenic, Serotonin, Transporters, SERT, 5-Hydroxytryptamine, Monoamine, Neurotransmitter, DAT, Methylenedioxymethamphetamine, hydrochloride, 92279-84-0, (±)-Methylenedioxymethamphetamine, Dopamine, 3027, Tocris Bioscience

Citations for (±)-MDMA hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for (±)-MDMA hydrochloride.

Reviews for (±)-MDMA hydrochloride

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Reinstatement of MDMA seeking by exposure to discrete drug-conditioned cues.
By Kevin Ball on 01/25/2019
Assay Type: In Vivo
Species: Rat

Rats self-administered MDMA (0.30 mg/kg/infusion, i.v.). We then showed that, following extinction of MDMA seeking, discrete MDMA-associated cues reinstated MDMA-seeking behavior. Also, the magnitude of reinstatement was positively correlated with the level of responding during MDMA self-administration.

PMID: 2067991 Reference
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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

5-HT Receptors Scientific Review

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.