DL-AP4 Sodium salt
Biological Activity
Sodium salt of the broad spectrum EAA ligand DL-AP4.
Technical Data
| M. Wt | 205.08 |
| Formula | C4H9NNaO5P |
| Storage | Desiccate at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 1263093-79-3 |
| PubChem ID | 52974248 |
| InChI Key | IGWPQOULJIILQQ-UHFFFAOYSA-M |
| Smiles | [Na+].NC(CCP(O)([O-])=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 20.51 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 205.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.88 mL | 24.38 mL | 48.76 mL |
| 5 mM | 0.98 mL | 4.88 mL | 9.75 mL |
| 10 mM | 0.49 mL | 2.44 mL | 4.88 mL |
| 50 mM | 0.1 mL | 0.49 mL | 0.98 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the biological activity of the product.
Evans et al (1979) Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br.J.Pharmacol. 67 591 PMID: 316343
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024
If you know of a relevant reference for DL-AP4 Sodium salt, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: DL-AP4 Sodium salt, DL-AP4 Sodium salt supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, mGlu, 3699, Tocris Bioscience
1 Citation for DL-AP4 Sodium salt
Citations are publications that use Tocris products. Selected citations for DL-AP4 Sodium salt include:
Zhou et al (2015) Autophagy supports color vision. Autophagy 11 1821 PMID: 26292183
Do you know of a great paper that uses DL-AP4 Sodium salt from Tocris? Please let us know.
Reviews for DL-AP4 Sodium salt
There are currently no reviews for this product. Be the first to review DL-AP4 Sodium salt and earn rewards!
Have you used DL-AP4 Sodium salt?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Ion Channel Product Listing
A collection of around 500 products for ion channel research, the listing includes research tools for the study of:
- Ligand-gated ion channels
- Voltage-gated ion channels
- Other Ion Channels
Pain Research Product Guide
A collection of over 250 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Epilepsy PosterNew
Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.
Pain Poster
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.
Parkinson's Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.
