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DL-AP4 Sodium salt

Cat. No. 3699 1 Citation Submit a Review Datasheet / COA / SDS
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Cat.No. 3699 - DL-AP4 Sodium salt | C4H9NNaO5P | CAS No. 1263093-79-3
Description: Broad spectrum glutamatergic antagonist; sodium salt of DL-AP4 (Cat. No. 0101)
Chemical Name: DL-2-Amino-4-phosphonobutyric acid sodium salt
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Sodium salt of the broad spectrum EAA ligand DL-AP4.

D-isomer and L-isomer also available.

Technical Data

M. Wt 205.08
Formula C4H9NNaO5P
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 1263093-79-3
PubChem ID 52974248
InChI Key IGWPQOULJIILQQ-UHFFFAOYSA-M
Smiles [Na+].NC(CCP(O)([O-])=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 20.51 100

Preparing Stock Solutions

The following data is based on the product molecular weight 205.08. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.88 mL 24.38 mL 48.76 mL
5 mM 0.98 mL 4.88 mL 9.75 mL
10 mM 0.49 mL 2.44 mL 4.88 mL
50 mM 0.1 mL 0.49 mL 0.98 mL

Molarity Calculator

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References

References are publications that support the biological activity of the product.

Evans et al (1979) Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br.J.Pharmacol. 67 591 PMID: 316343

Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024

If you know of a relevant reference for DL-AP4 Sodium salt, please let us know.

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Keywords: DL-AP4 Sodium salt, DL-AP4 Sodium salt supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, mGlu, 3699, Tocris Bioscience

1 Citation for DL-AP4 Sodium salt

Citations are publications that use Tocris products. Selected citations for DL-AP4 Sodium salt include:

Zhou et al (2015) Autophagy supports color vision. Autophagy 11 1821 PMID: 26292183

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