DL-AP4 Sodium salt

Pricing Availability   Qty
Cat.No. 3699 - DL-AP4 Sodium salt | C4H9NNaO5P | CAS No. 1263093-79-3
Description: Broad spectrum EAA antagonist. Sodium salt of DL-AP4 (Cat. No. 0101)
Chemical Name: DL-2-Amino-4-phosphonobutyric acid sodium salt
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

Sodium salt of the broad spectrum EAA ligand DL-AP4.

D-isomer and L-isomer also available.

Technical Data

M. Wt 205.08
Formula C4H9NNaO5P
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 1263093-79-3
PubChem ID 52974248
InChI Key IGWPQOULJIILQQ-UHFFFAOYSA-M
Smiles [Na+].NC(CCP(O)([O-])=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 20.51 100

Preparing Stock Solutions

The following data is based on the product molecular weight 205.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.88 mL 24.38 mL 48.76 mL
5 mM 0.98 mL 4.88 mL 9.75 mL
10 mM 0.49 mL 2.44 mL 4.88 mL
50 mM 0.1 mL 0.49 mL 0.98 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References

References are publications that support the biological activity of the product.

Evans et al (1979) Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br.J.Pharmacol. 67 591 PMID: 316343

Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024


If you know of a relevant reference for DL-AP4 Sodium salt, please let us know.

View Related Products by Product Action

View all Non-selective Ionotropic Glutamate Antagonists

Keywords: DL-AP4 Sodium salt, DL-AP4 Sodium salt supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, mGlu, 3699, Tocris Bioscience

1 Citation for DL-AP4 Sodium salt

Citations are publications that use Tocris products. Selected citations for DL-AP4 Sodium salt include:

Zhou et al (2015) Autophagy supports color vision. Autophagy 11 1821 PMID: 26292183


Do you know of a great paper that uses DL-AP4 Sodium salt from Tocris? Please let us know.

Reviews for DL-AP4 Sodium salt

There are currently no reviews for this product. Be the first to review DL-AP4 Sodium salt and earn rewards!

Have you used DL-AP4 Sodium salt?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Ion Channel

Ion Channel Product Listing

A collection of around 500 products for ion channel research, the listing includes research tools for the study of:

  • Ligand-gated ion channels
  • Voltage-gated ion channels
  • Other Ion Channels
Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Epilepsy

Epilepsy Poster

Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.

Pain

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

Parkinson's

Parkinson's Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.