(±)-ACPT-III

Discontinued Product

Unfortunately (±)-ACPT-III (Cat. No. 1113) has been withdrawn from sale for commercial reasons.
Cat.No. 1113 - (±)-ACPT-III | C8H11NO6
Description: Selective group III agonist
Chemical Name: (3RS,4RS)-1-Aminocyclopentane-1,3,4-tricarboxylic acid
Datasheet
Citations
Literature

Biological Activity

A selective group III metabotropic receptor agonist displaying EC50 values of 40 μM at mGlu4a receptors and > 1 mM at mGlu1a and mGlu2 receptors.

Licensing Information

Sold with the permission of the CNRS.

Technical Data

M. Wt 217.18
Formula C8H11NO6
Storage Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 217.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.6 mL 23.02 mL 46.04 mL
5 mM 0.92 mL 4.6 mL 9.21 mL
10 mM 0.46 mL 2.3 mL 4.6 mL
50 mM 0.09 mL 0.46 mL 0.92 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Acher et al (1997) Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor.subtypes J.Med.Chem. 40 3119 PMID: 9301676

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Keywords: (±)-ACPT-III, supplier, Glutamate, (Metabotropic), Group, III, Receptors, Tocris Bioscience

Citations for (±)-ACPT-III

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Currently there are no citations for (±)-ACPT-III.

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Reviews

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Literature in this Area

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Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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Pathways for (±)-ACPT-III

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