Discontinued Product

DEA (Cat. No. 1485) has been withdrawn from sale for commercial reasons.
Cat.No. 1485 - DEA | C24H41NO2 | CAS No. 150314-35-5
Description: Endogenous CB1 agonist
Alternative Names: Docosatetraenylethanolamide
Chemical Name: N-(2-Hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenamide
Literature (6)

Biological Activity for DEA

DEA is a potent endocannabinoid and anandamide (Cat. No. 1339) analog that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (Ki = 34.4 nM). Cannabimimetic in vivo.

Technical Data for DEA

M. Wt 375.59
Formula C24H41NO2
Storage Desiccate at -20°C
CAS Number 150314-35-5
PubChem ID 5282273

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for DEA

References are publications that support the biological activity of the product.

Barg et al (1995) Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. Eur.J.Pharmacol. 287 145 PMID: 8749028

Hanus et al (1993) Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J.Med.Chem. 36 3032 PMID: 8411021

Walter et al (2001) Microglial cells produce endocannabinoids and express functional cannabinoid receptors: evidence that docosatetraenylethanolamide (DEA) is an additional endocannabinoid. Soc.Neurosci.Abstr. 634.16

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Keywords: DEA, DEA supplier, Endogenous, CB1, agonists, Cannabinoids, Receptors, cb1r, Docosatetraenylethanolamide, 1485, Tocris Bioscience

Citations for DEA

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Currently there are no citations for DEA.

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