Home / Cell Biology / Signal Transduction / Cytokine and NF-κB Signaling / Cytokines / (D)-(+)-Neopterin

(D)-(+)-Neopterin

Cat. No. 4656 1 Citation Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Stimulated by IFN-γ; marker of immune activation
Chemical Name: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (2)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for (D)-(+)-Neopterin

(D)-(+)-Neopterin is a precursor of biopterin synthesis. Synthesized in response to interferon-γ stimulation; used as a marker of T helper cell-induced immune activation. Also an indicator of oxidative stress; modulates the effects of reactive oxygen species (ROS).

Compound Libraries for (D)-(+)-Neopterin

(D)-(+)-Neopterin is also offered as part of the Tocriscreen Antiviral Library. Find out more about compound libraries available from Tocris.

Technical Data for (D)-(+)-Neopterin

M. Wt 253.21
Formula C9H11N5O4
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2009-64-5
PubChem ID 448839
InChI Key BMQYVXCPAOLZOK-XINAWCOVSA-N
Smiles OC[C@@H](O)[C@@H](O)C2=NC1=C(N=C2)N=C(N)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for (D)-(+)-Neopterin

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 5.06 20 with gentle warming

Preparing Stock Solutions for (D)-(+)-Neopterin

The following data is based on the product molecular weight 253.21. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 19.75 mL 98.73 mL 197.46 mL
1 mM 3.95 mL 19.75 mL 39.49 mL
2 mM 1.97 mL 9.87 mL 19.75 mL
10 mM 0.39 mL 1.97 mL 3.95 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets for (D)-(+)-Neopterin

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References for (D)-(+)-Neopterin

References are publications that support the biological activity of the product.

Murr et al (2002) Neopterin as a marker for immune system activation. Curr.Drug Metab. 3 175 PMID: 12003349

Huber et al (1984) Immune response-associated production of neopterin. J.Exp.Med. 160 310 PMID: 6429267

If you know of a relevant reference for (D)-(+)-Neopterin, please let us know.

View Related Products by Target

Keywords: (D)-(+)-Neopterin, (D)-(+)-Neopterin supplier, cytokines, IFN-gamma, IFN-g, IFN-γ, immune, markers, oxidative, stress, indicators, Cytokines, 4656, Tocris Bioscience

1 Citation for (D)-(+)-Neopterin

Citations are publications that use Tocris products. Selected citations for (D)-(+)-Neopterin include:

Kaminska et al (2016) Highly efficient SERS-based detection of cerebrospinal fluid neopterin as a diagnostic marker of bacterial infection. J Neurochem 408 4319 PMID: 27086021

Do you know of a great paper that uses (D)-(+)-Neopterin from Tocris? Please let us know.

Reviews for (D)-(+)-Neopterin

There are currently no reviews for this product. Be the first to review (D)-(+)-Neopterin and earn rewards!

Have you used (D)-(+)-Neopterin?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Rheumatoid Arthritis Poster

Rheumatoid Arthritis Poster

Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.