Discontinued Product

Unfortunately Cypermethrin (Cat. No. 0872) has been withdrawn from sale for commercial reasons.
Cat.No. 0872 - Cypermethrin | C22H19Cl2NO3 | CAS No. 52315-07-8
Description: Calcineurin inhibitor (protein phosphatase 2B)
Chemical Name: 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester

Biological Activity

Type II synthetic pyrethroid insecticide; an extremely potent, cell-permeable inhibitor of calcineurin.

Technical Data

M. Wt 416.3
Formula C22H19Cl2NO3
Storage Desiccate at +4°C
CAS Number 52315-07-8
Smiles O=C(C3C(C)(C)C3/C=C(Cl)/Cl)OC(C#N)C1=CC(OC2=CC=CC=C2)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 416.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.4 mL 12.01 mL 24.02 mL
5 mM 0.48 mL 2.4 mL 4.8 mL
10 mM 0.24 mL 1.2 mL 2.4 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Enan and Matsumara (1992) Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. Biochem.Pharmacol. 43 1777 PMID: 1315545

Richter et al (1995) Growth inhibitory effects of FK 506 and cyclosporin A independent of inhibition of calcineurin. Biochem.Pharmacol. 49 367 PMID: 7531976

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Keywords: Cypermethrin, supplier, Calcineurin, inhibitors, inhibits, protein, phosphatase, 2B, Protein, Ser/Thr, Phosphatases, Protein, Ser/Thr, Phosphatases, Protein, Ser/Thr, Phosphatases, Tocris Bioscience

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