CycLuc 1

Pricing Availability   Qty
Cat.No. 6823 - CycLuc 1 | C13H11N3O2S2 | CAS No. 1247879-16-8
Description: Synthetic luciferase substrate; brain penetrant; displays NIR emission
Chemical Name: (4S)-2-(6,7-Dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-4-thiazolecarboxylic acid
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)

Biological Activity for CycLuc 1

CycLuc 1 is a synthetic luciferase substrate. Displays near-infrared (NIR) emission; peak luminescence at 599 nm. Suitable for use in in vivo bioluminescence imaging. Brain penetrant.

Optical Data for CycLuc 1

CycLuc 1 Dye Spectra
Emission Color Orange
λem 600 nm
Application bioluminescence imaging BLI

Technical Data for CycLuc 1

M. Wt 305.37
Formula C13H11N3O2S2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1247879-16-8
PubChem ID 91885395
InChI Key HBZBAMXERPYTFS-SECBINFHSA-N
Smiles OC([C@H]1CSC(C2=NC3=C(C=C4NCCC4=C3)S2)=N1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CycLuc 1

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.54 100

Preparing Stock Solutions for CycLuc 1

The following data is based on the product molecular weight 305.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.27 mL 16.37 mL 32.75 mL
5 mM 0.65 mL 3.27 mL 6.55 mL
10 mM 0.33 mL 1.64 mL 3.27 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

References for CycLuc 1

References are publications that support the biological activity of the product.

Reddy et al (2010) Robust light emission from cyclic alkylaminoluciferin substrates for firefly luciferase. J.Am.Chem.Soc. 132 13586 PMID: 20828122

Evans et al (2014) A synthetic luciferin improves bioluminescence imaging in live mice. Nat.Methods. 11 393 PMID: 24509630


If you know of a relevant reference for CycLuc 1, please let us know.

View Related Products by Target

Keywords: CycLuc 1, CycLuc 1 supplier, CycLuc1, luciferase, substrate, near, infrared, NIR, emission, bioluminescence, imaging, Bioluminescent, Substrates, 6823, Tocris Bioscience

Citations for CycLuc 1

Citations are publications that use Tocris products.

Currently there are no citations for CycLuc 1. Do you know of a great paper that uses CycLuc 1 from Tocris? Please let us know.

Reviews for CycLuc 1

There are currently no reviews for this product. Be the first to review CycLuc 1 and earn rewards!

Have you used CycLuc 1?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Fluorescent Probes and Dyes Research Product Guide

Fluorescent Probes and Dyes Research Product Guide

This product guide provides a background to the use of Fluorescent Probes and Dyes, as well as a comprehensive list of our

  • Fluorescent Dyes
  • Dyes for Flow Cytometry
  • Fluorescent Probes
  • Anti-fade Reagents
  • Bioluminescent Substrates
  • Fluorogenic Dyes for Light-Up Aptamers
  • Fluorescent Probes for Imaging Bacteria
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals