You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Cyclapolin 9
Cyclapolin 9 is a selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC50 = 500 nM).
Technical Data for Cyclapolin 9
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Cyclapolin 9
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Cyclapolin 9
The following data is based on the product molecular weight 307.21. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||13.02 mL||65.1 mL||130.2 mL|
|1.25 mM||2.6 mL||13.02 mL||26.04 mL|
|2.5 mM||1.3 mL||6.51 mL||13.02 mL|
|12.5 mM||0.26 mL||1.3 mL||2.6 mL|
References for Cyclapolin 9
References are publications that support the biological activity of the product.
Taylor et al (2008) Ligand discovery and virtual screening using the program LIDAEUS. Br.J.Pharmacol. 153 S55 PMID: 18037921
McInnes et al (2006) Inhibitors of polo-like kinase reveal roles in spindle pole maintenance. Nature Chem.Biol. 2 608
If you know of a relevant reference for Cyclapolin 9, please let us know.
View Related Products by Product Action
Keywords: Cyclapolin 9, Cyclapolin 9 supplier, Selective, ATP-competitive, PLK1, inhibitors, inhibits, Polo-like, Kinase, Kinases, Cyclapolin9, Mitosis, 3116, Tocris Bioscience
1 Citation for Cyclapolin 9
Citations are publications that use Tocris products. Selected citations for Cyclapolin 9 include:
Cozzoli et al (2012) Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures. Proc Natl Acad Sci U S A 36 1623 PMID: 22432643
Do you know of a great paper that uses Cyclapolin 9 from Tocris? Please let us know.
Reviews for Cyclapolin 9
There are currently no reviews for this product. Be the first to review Cyclapolin 9 and earn rewards!
Have you used Cyclapolin 9?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cell Cycle and DNA Damage Research Product Guide
This product guide provides a review of the cell cycle and DNA damage research area and lists over 170 products, including research tools for:
- Cell Cycle and Mitosis
- DNA Damage Repair
- Targeted Protein Degradation
- Ubiquitin Proteasome Pathway
- Chemotherapy Targets
Cell Cycle & DNA Damage Repair PosterUpdated
In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. Adapted from the 2015 Cancer Product Guide, Edition 3, this poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.