Selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC50 = 500 nM).
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 307.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.26 mL||16.28 mL||32.55 mL|
|5 mM||0.65 mL||3.26 mL||6.51 mL|
|10 mM||0.33 mL||1.63 mL||3.26 mL|
|50 mM||0.07 mL||0.33 mL||0.65 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Taylor et al (2008) Ligand discovery and virtual screening using the program LIDAEUS. Br.J.Pharmacol. 153 S55 PMID: 18037921
If you know of a relevant reference for Cyclapolin 9, please let us know.
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Keywords: Selective ATP-competitive PLK1 inhibitors inhibits Polo-like Kinase Kinases Cyclapolin9 Polo-like Kinase
1 Citation for Cyclapolin 9
Citations are publications that use Tocris products. Selected citations for Cyclapolin 9 include:
Cozzoli et al (2012) Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures. Proc Natl Acad Sci U S A 36 1623 PMID: 22432643
Do you know of a great paper that uses Cyclapolin 9 from Tocris? If so please let us know.
Literature in this Area
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