You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). Exhibits anxiolytic effects in rat models.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 465.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.15 mL||10.74 mL||21.48 mL|
|5 mM||0.43 mL||2.15 mL||4.3 mL|
|10 mM||0.21 mL||1.07 mL||2.15 mL|
|50 mM||0.04 mL||0.21 mL||0.43 mL|
References are publications that support the biological activity of the product.
Overstreet et al (2009) A selective ALDH-2 inhibitor reduces anxiety in rats. Pharmacol.Biochem.Behav. 94 255 PMID: 19747934
Yao et al (2010) Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of DA synthesis. Nat.Med. 16 1024 PMID: 20729865
If you know of a relevant reference for CVT 10216, please let us know.
View Related Products by Product Action
Keywords: CVT 10216, CVT 10216 supplier, CVT10216, potent, selective, reversible, inhibitors, inhibits, aldehyde, dehydrogenase, 2, ALDH2, anxiolytics, anti-anxiety, Aldehyde, Dehydrogenase, 5164, Tocris Bioscience
Citations for CVT 10216
Citations are publications that use Tocris products.
Currently there are no citations for CVT 10216. Do you know of a great paper that uses CVT 10216 from Tocris? Please let us know.
Reviews for CVT 10216
There are currently no reviews for this product. Be the first to review CVT 10216 and earn rewards!
Have you used CVT 10216?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]New
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells