CL 82198 hydrochloride
Selective inhibitor of MMP-13 (89% inhibition at 10 μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 338.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.95 mL||14.76 mL||29.51 mL|
|5 mM||0.59 mL||2.95 mL||5.9 mL|
|10 mM||0.3 mL||1.48 mL||2.95 mL|
|50 mM||0.06 mL||0.3 mL||0.59 mL|
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References are publications that support the products' biological activity.
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Keywords: Selective inhibitors inhibits MMP-13 Matrixins Matrix Metalloproteinase MMP Metalloprotease Proteinases Proteases CL82198 hydrochloride Matrix Metalloprotease
1 Citation for CL 82198 hydrochloride
Citations are publications that use Tocris products. Selected citations for CL 82198 hydrochloride include:
Wang et al (2013) MMP13 is a critical target gene during the progression of osteoarthritis. J Neurosci 15 R5 PMID: 23298463
Do you know of a great paper that uses CL 82198 hydrochloride from Tocris? If so please let us know.