ci-IP3/PM

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Cat.No. 6210 - ci-IP3/PM | C42H64NO31P3 | CAS No. 1009832-82-9
Description: Caged inositol triphosphate
Chemical Name: 6-O-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-2,3-O-(1-methylethylidene)-D-myo-Inositol 1,4,5-tris[bis[(1-oxopropoxy)methyl]phosphate]
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores.

F 127 (Cat. No. 6253) for the solubilization of ci-IP3/PM is also available.

Technical Data

M. Wt 1171.87
Formula C42H64NO31P3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1009832-82-9
PubChem ID 124221754
InChI Key FNWIHZJMPHUCAI-RJQNPCEJSA-N
Smiles CC(O1)(C)O[C@H]([C@H]1[C@@H](OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H]2OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H](OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H]2OCC3=CC(OC)=C(OC)C=C3[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble in DMSO

References

References are publications that support the biological activity of the product.

Dakin and Li et al (2007) Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate. Cell Calcium 42 291 PMID: 17307252

Lock et al (2017) Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3. Cell Calcium PMID: 28108028

Zhang et al (2004) Endothelin-1 and IP3 induced Ca2+ sparks in pulmonary arterial smooth muscle cells. J.Cardiovasc.Pharmacol. 44 S121 PMID: 15838259


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Keywords: ci-IP3/PM, ci-IP3/PM supplier, Caged, IP3, activated, intracellular, Ca2+, calcium, stores, photolysis, UV, inositol, triphosphate, Second, Messenger, Compounds, Receptors, 6210, Tocris Bioscience

Citations for ci-IP3/PM

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Literature in this Area

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