Caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores.
F 127 (Cat. No. 6253) for the solubilization of ci-IP3/PM is also available.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO|
References are publications that support the biological activity of the product.
Dakin and Li et al (2007) Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate. Cell Calcium 42 291 PMID: 17307252
Lock et al (2017) Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3. Cell Calcium PMID: 28108028
Zhang et al (2004) Endothelin-1 and IP3 induced Ca2+ sparks in pulmonary arterial smooth muscle cells. J.Cardiovasc.Pharmacol. 44 S121 PMID: 15838259
If you know of a relevant reference for ci-IP3/PM, please let us know.
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Keywords: ci-IP3/PM, ci-IP3/PM supplier, Caged, IP3, activated, intracellular, Ca2+, calcium, stores, photolysis, UV, inositol, triphosphate, Second, Messenger, Compounds, Receptors, 6210, Tocris Bioscience
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