Caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO|
Preparing Stock Solutions
The following data is based on the product molecular weight 1171.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.85 mL||4.27 mL||8.53 mL|
|5 mM||0.17 mL||0.85 mL||1.71 mL|
|10 mM||0.09 mL||0.43 mL||0.85 mL|
|50 mM||0.02 mL||0.09 mL||0.17 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Dakin and Li et al (2007) Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate. Cell Calcium 42 291 PMID: 17307252
Lock et al (2017) Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3. Cell Calcium PMID: 28108028
Zhang et al (2004) Endothelin-1 and IP3 induced Ca2+ sparks in pulmonary arterial smooth muscle cells. J.Cardiovasc.Pharmacol. 44 S121 PMID: 15838259
If you know of a relevant reference for ci-IP3/PM, please let us know.
Keywords: Caged IP3 activated intracellular Ca2+ calcium stores photolysis UV inositol triphosphate Caged Compounds
Citations for ci-IP3/PM
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Literature in this Area
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