ci-IP3/PM

Pricing Availability Delivery Time Qty
Cat.No. 6210 - ci-IP3/PM | C42H64NO31P3 | CAS No. 1009832-82-9
Description: Caged inositol triphosphate
Chemical Name: 6-O-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-2,3-O-(1-methylethylidene)-D-myo-Inositol 1,4,5-tris[bis[(1-oxopropoxy)methyl]phosphate]
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores.

Technical Data

M. Wt 1171.87
Formula C42H64NO31P3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1009832-82-9
PubChem ID 124221754
InChI Key FNWIHZJMPHUCAI-RJQNPCEJSA-N
Smiles CC(O1)(C)O[C@H]([C@H]1[C@@H](OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H]2OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H](OP(OCOC(CC)=O)(OCOC(CC)=O)=O)[C@@H]2OCC3=CC(OC)=C(OC)C=C3[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in DMSO

Preparing Stock Solutions

The following data is based on the product molecular weight 1171.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.85 mL 4.27 mL 8.53 mL
5 mM 0.17 mL 0.85 mL 1.71 mL
10 mM 0.09 mL 0.43 mL 0.85 mL
50 mM 0.02 mL 0.09 mL 0.17 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Dakin and Li et al (2007) Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate. Cell Calcium 42 291 PMID: 17307252

Lock et al (2017) Comparison of Ca2+ puffs evoked by extracellular agonists and photoreleased IP3. Cell Calcium PMID: 28108028

Zhang et al (2004) Endothelin-1 and IP3 induced Ca2+ sparks in pulmonary arterial smooth muscle cells. J.Cardiovasc.Pharmacol. 44 S121 PMID: 15838259


If you know of a relevant reference for ci-IP3/PM, please let us know.

View Related Products by Target

Keywords: Caged IP3 activated intracellular Ca2+ calcium stores photolysis UV inositol triphosphate Caged Compounds

Citations for ci-IP3/PM

Citations are publications that use Tocris products.

Currently there are no citations for ci-IP3/PM. Do you know of a great paper that uses ci-IP3/PM from Tocris? If so please let us know.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for ci-IP3/PM

Protocols

TODO: Add Protocols