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Biological Activity for Chaetoglobosin A
Chaetoglobosin A is an antibiotic; preferentially induces apoptosis in chronic lymphocytic leukemia (CLL) cells over normal B cells. Inhibits actin polymerization and leads to the accumulation of cells in G2 phase.
Technical Data for Chaetoglobosin A
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Chaetoglobosin A
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Chaetoglobosin A
The following data is based on the product molecular weight 528.64. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.89 mL||9.46 mL||18.92 mL|
|5 mM||0.38 mL||1.89 mL||3.78 mL|
|10 mM||0.19 mL||0.95 mL||1.89 mL|
|50 mM||0.04 mL||0.19 mL||0.38 mL|
Product Datasheets for Chaetoglobosin A
References for Chaetoglobosin A
References are publications that support the biological activity of the product.
Knudsen et al (2014) Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 28 1289 PMID: 24280868
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Citations for Chaetoglobosin A
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Reviews for Chaetoglobosin A
Average Rating: 5 (Based on 1 Review.)
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