Canrenone

Pricing Availability Delivery Time Qty
Cat.No. 3281 - Canrenone | C22H28O3 | CAS No. 976-71-6
Description: Mineralocorticoid receptor antagonist
Chemical Name: (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid γ-lactone
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Mineralocorticoid receptor antagonist. Active metabolite of spironolactone (Cat. No. 2968).

Technical Data

M. Wt 340.46
Formula C22H28O3
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 976-71-6
PubChem ID 13789
InChI Key UJVLDDZCTMKXJK-WNHSNXHDSA-N
Smiles O=C1CC[C@@]2(C)C(C=C[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@]54OC(CC5)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.05 100

Preparing Stock Solutions

The following data is based on the product molecular weight 340.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.94 mL 14.69 mL 29.37 mL
5 mM 0.59 mL 2.94 mL 5.87 mL
10 mM 0.29 mL 1.47 mL 2.94 mL
50 mM 0.06 mL 0.29 mL 0.59 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Delyani et al (2000) Mineralocorticoid receptor antagonists: the evolution of utility and pharmacology. Kidney Int. 57 1408 PMID: 10760075


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Citations for Canrenone

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