Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE, Cat. No. 1927).
(Modifications: Tyr-1 = N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-)-pTyr, Glu-2 = αGlu, Glu-3 = αGlu)
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 923.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.08 mL||5.41 mL||10.82 mL|
|5 mM||0.22 mL||1.08 mL||2.16 mL|
|10 mM||0.11 mL||0.54 mL||1.08 mL|
|50 mM||0.02 mL||0.11 mL||0.22 mL|
References are publications that support the products' biological activity.
Park et al (2002) Design and characterization of non-phosphopeptide inhibitors for src family SH2 domains. Bioorg.Med.Chem.Lett. 12 2711 PMID: 12217360
If you know of a relevant reference for Caffeic acid-pYEEIE, please let us know.
View Related Products by Product Action
Keywords: Caffeic acid-pYEEIE, supplier, Phosphopeptide, ligands, src, SH2, domain, Kinases, Src, Kinases, Src, Kinases, Tocris Bioscience
1 Citation for Caffeic acid-pYEEIE
Citations are publications that use Tocris products. Selected citations for Caffeic acid-pYEEIE include:
Xie et al (2015) A selective NMR probe to monitor the conformational transition from inactive to active kinase. J Neurosci 10 262 PMID: 25248068
Do you know of a great paper that uses Caffeic acid-pYEEIE from Tocris? If so please let us know.
Reviews for Caffeic acid-pYEEIE
There are currently no reviews for this product. Be the first to review Caffeic acid-pYEEIE and earn rewards!
Have you used Caffeic acid-pYEEIE?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review