Caffeic acid-pYEEIE
![Cat.No. 1935 - Caffeic acid-pYEEIE | N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-)-pTyr-α-Glu-α-Glu-Ile-Glu | CAS No. 507471-72-9](http://resources.tocris.com/images/datasheets/structures/caffeic-acid-pyeeie_1935.png "Cat.No. 1935 - Caffeic acid-pYEEIE | N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-)-pTyr-α-Glu-α-Glu-Ile-Glu | CAS No. 507471-72-9")
Biological Activity
Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE, Cat. No. 1927).
Technical Data
| M. Wt | 923.82 |
| Formula | C39H50N5O19P |
| Sequence |
YEEIE (Modifications: Tyr-1 = N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-)-pTyr, Glu-2 = αGlu, Glu-3 = αGlu) |
| Storage | Desiccate at -20°C |
| CAS Number | 507471-72-9 |
| PubChem ID | 90488727 |
| InChI Key | OLKLXQPYJYPETQ-GYHHIBSGSA-N |
| Smiles | CCC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC(=O)\C=C\C1=CC=C(O)C(O)=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
Please contact Customer Service
References
References are publications that support the biological activity of the product.
Park et al (2002) Design and characterization of non-phosphopeptide inhibitors for src family SH2 domains. Bioorg.Med.Chem.Lett. 12 2711 PMID: 12217360
If you know of a relevant reference for Caffeic acid-pYEEIE, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Caffeic acid-pYEEIE, Caffeic acid-pYEEIE supplier, Phosphopeptide, ligands, src, SH2, domain, Kinases, Src, 1935, Tocris Bioscience
1 Citation for Caffeic acid-pYEEIE
Citations are publications that use Tocris products. Selected citations for Caffeic acid-pYEEIE include:
Xie et al (2015) A selective NMR probe to monitor the conformational transition from inactive to active kinase. J Neurosci 10 262 PMID: 25248068
Do you know of a great paper that uses Caffeic acid-pYEEIE from Tocris? Please let us know.
Reviews for Caffeic acid-pYEEIE
There are currently no reviews for this product. Be the first to review Caffeic acid-pYEEIE and earn rewards!
Have you used Caffeic acid-pYEEIE?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Research Product Guide
A collection of over 750 products for cancer research, the guide includes research tools for the study of:
- Cancer Metabolism
- Epigenetics in Cancer
- Receptor Signaling
- Cell Cycle and DNA Damage Repair
- Angiogenesis
- Invasion and Metastasis
Immunology Product Listing
A collection of over 190 products for immunology research, the guide includes research tools for the study of:
- Chemokine and Cytokine Signaling
- Chemotaxis
- Complement System
- Immune Cell Signaling
- Inflammation
Kinases Product Listing
A collection of over 400 products for kinase research, the listing includes inhibitors of:
- Receptor Tyrosine Kinases
- Protein Kinases A, C, D and G
- PI-3 Kinase, Akt and mTOR
- MAPK Signaling
- Receptor Serine/Threonine Kinases
