Buprenorphine hydrochloride

Pricing Availability Delivery Time Qty
Cat.No. 2808 - Buprenorphine hydrochloride | C29H41NO4.HCl | CAS No. 53152-21-9
Description: Opioid receptor ligand
Chemical Name: [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

ORL1 receptor agonist that also displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors.

Technical Data

M. Wt 504.1
Formula C29H41NO4.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 53152-21-9
PubChem ID 9848989
InChI Key UAIXRPCCYXNJMQ-HPRIMLMLSA-N
Smiles OC1=CC=C3C2=C1O[C@@H]([C@@]7(OC)[C@]([C@@](C)(C(C)(C)C)O)([H])C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 25.2 50
water 12.6 25

Preparing Stock Solutions

The following data is based on the product molecular weight 504.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.98 mL 9.92 mL 19.84 mL
5 mM 0.4 mL 1.98 mL 3.97 mL
10 mM 0.2 mL 0.99 mL 1.98 mL
50 mM 0.04 mL 0.2 mL 0.4 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Wnendt et al (1999) Agonist effect of buprenorphine in a nociceptin/OFQ receptor-triggered reporter gene assay. Mol.Pharmacol. 56 334 PMID: 10419552

Tzschentke (2002) Behavioral pharmacology of buprenorphine, with a focus on preclinical models of reward and addiction. Psychopharmacology 161 1 PMID: 11967625


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Keywords: Opioids receptors ligands Receptors Miscellaneous/Non-selective Opioids

Citations for Buprenorphine hydrochloride

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Pathways for Buprenorphine hydrochloride

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