A potent dopamine re-uptake inhibitor with a behavioral profile different from that of PCP and similar to that of cocaine.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 415.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.41 mL||12.03 mL||24.06 mL|
|5 mM||0.48 mL||2.41 mL||4.81 mL|
|10 mM||0.24 mL||1.2 mL||2.41 mL|
|50 mM||0.05 mL||0.24 mL||0.48 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Chergui et al (1992) Inhibition of the locus coeruleus neurons by the phenylcyclidine analog, N-[1-(2-benzo(b thiophenyl)cyclohexyl]-piperidine: evidence for potent indirect adrenoceptor agonist properties. Eur.J.Pharmacol. 219 169 PMID: 1397045
Koek et al (1989) The phencyclidine (PCP) analogue N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioural effects with PCP, ketamine and MK-801. J.Pharmacol.Exp.Ther. 250 1019 PMID: 2674416
Vignon et al (1988) [3H]N-[1-(2-benzo[b]thiophenyl)cyclohexyl]piperidine ([3H]BTCP): a new phencyclidine analogue selective for the dopamine uptake complex. Eur.J.Pharmacol. 148 427 PMID: 3384005
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Keywords: Potent dopamine reuptake inhibitors inhibits DAT Transporters Monoamine Neurotransmitter Dopamine Transporters
Citations for BTCP maleate
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Literature in this Area
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
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