You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for BTB1
BTB1 is a selective and ATP-competitive mitotic kinesin Kif18A inhibitor (IC50 = 1.7 μM); reversibly inhibits microtubule-stimulated Kif18A ATPase activity. Displays selectivity against a panel of other mitotic kinesins.
Technical Data for BTB1
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for BTB1
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for BTB1
The following data is based on the product molecular weight 297.71. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.36 mL||16.79 mL||33.59 mL|
|5 mM||0.67 mL||3.36 mL||6.72 mL|
|10 mM||0.34 mL||1.68 mL||3.36 mL|
|50 mM||0.07 mL||0.34 mL||0.67 mL|
References for BTB1
References are publications that support the biological activity of the product.
Braun et al (2014) Synthesis and biological evaluation of optimized Inhibitors of the mitotic kinesin Kif18A. ACS Chem.Biol. 10 554 PMID: 25402598
Catarinella et al (2009) BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A. Angew.Chem.Int.Ed.Engl. 48 9072 PMID: 19856362
If you know of a relevant reference for BTB1, please let us know.
View Related Products by Product Action
Keywords: BTB1, BTB1 supplier, Selective, reversible, ATP-competitive, mitotic, Kinesins, Kif18A, inhibitors, inhibits, microtubule, mitosis, Kinesin, Mitosis, 5399, Tocris Bioscience
Citations for BTB1
Citations are publications that use Tocris products.
Currently there are no citations for BTB1. Do you know of a great paper that uses BTB1 from Tocris? Please let us know.
Reviews for BTB1
There are currently no reviews for this product. Be the first to review BTB1 and earn rewards!
Have you used BTB1?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.