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ATP non-competitive kinesin Eg5 inhibitor. Selectively inhibits microtubule-bound Eg5. Inhibits multiple myeloma cell growth (IC50 = 2.2 μM).
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Chattopadhyay et al (2015) Niche-based screening in multiple myeloma identifies a kinesin-5 inhibitor with improved selectivity over hematopoietic progenitors. Cell Rep. 10 755 PMID: 25660025
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Keywords: BRD 9876, BRD 9876 supplier, BRD9876, ATP, non-competitive, kinesin-5, Eg5, inhibitors, inhibits, microtubule-bound, Kinesin, Mitosis, 5454, Tocris Bioscience
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