Bioymifi

Discontinued Product

Bioymifi (Cat. No. 5372) has been withdrawn from sale for commercial reasons.
Cat.No. 5372 - Bioymifi | C22H12BrN3O4S | CAS No. 1420071-30-2
Description: DR5 (TRAIL receptor) agonist; induces apoptosis
Chemical Name: 5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione
Purity: ≥97% (HPLC)
Datasheet
Citations
Reviews
Literature (3)

Biological Activity for Bioymifi

Bioymifi is a DR5 (TRAIL receptor) agonist. Directly binds extracellular domain of DR5 (Kd = 1.2 μM) and induces the formation of DR5 aggregates. Induces apoptosis of glioblastoma cells.

Technical Data for Bioymifi

M. Wt 494.32
Formula C22H12BrN3O4S
Storage Store at +4°C
Purity ≥97% (HPLC)
CAS Number 1420071-30-2
PubChem ID 70678419
InChI Key ULBOWKXOFOTCMU-NLDKGBHCSA-N
Smiles BrC1=CC=C(N3C(/C(SC3=N)=C/C2=CC=C(C4=CC=C(C(NC5=O)=O)C5=C4)O2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Bioymifi

References are publications that support the biological activity of the product.

Wang et al (2013) Small-molecule activation of the TRAIL receptor DR5 in human cancer cells. Nat.Chem.Biol. 9 84 PMID: 23292651

View Related Products by Product Action

View all Cytokine Receptor Agonists

Keywords: Bioymifi, Bioymifi supplier, TRAIL, tumor, necrosis, factor-related, apoptosis-inducing, ligand, DR5, TNF, agonists, agonism, Cytokine, Receptors, Apoptosis, Inducers, 5372, Tocris Bioscience

Citations for Bioymifi

Citations are publications that use Tocris products.

Currently there are no citations for Bioymifi.

Reviews for Bioymifi

There are currently no reviews for this product. Be the first to review Bioymifi and earn rewards!

Have you used Bioymifi?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Immunology Product Listing

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation
Pain Poster

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.