β-Alanine

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Cat.No. 0206 - beta-Alanine | C3H7NO2 | CAS No. 107-95-9
Description: Endogenous glycine agonist, more selective than taurine (Cat. No. 0209)
Datasheet
Citations
Literature

Biological Activity

Non-specific endogenous agonist at the inhibitory glycine receptor. More selective than taurine (Cat. No. 0209). Also distinguishes between GABA transporters (IC50 values are 19, 58, 110, 1320 and 5690 μM for rGAT-2, hGAT-3, rGAT-3, hBGT-3 and hGAT-1 respectively).

Technical Data

M. Wt 89.09
Formula C3H7NO2
Storage Store at RT
CAS Number 107-95-9
PubChem ID 239
InChI Key UCMIRNVEIXFBKS-UHFFFAOYSA-N
Smiles NCCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 89.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 11.22 mL 56.12 mL 112.25 mL
5 mM 2.24 mL 11.22 mL 22.45 mL
10 mM 1.12 mL 5.61 mL 11.22 mL
50 mM 0.22 mL 1.12 mL 2.24 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Borden et al (1994) Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur.J.Pharmacol. 269 219 PMID: 7851497

Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165 PMID: 7812607

Schieden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919 PMID: 7476923


If you know of a relevant reference for β-Alanine, please let us know.

View Related Products by Product Action

View all Glycine Receptor Agonists

Keywords: Endogenous glycine agonists selective Taurine GABA uptake inhibitors inhibits GAT-2 -3 receptor GlyR Glycine Receptors BGT-1 GAT Transporters Monoamine Neurotransmitter beta-alanine β-alanine Glycine Receptors

Citations for β-Alanine

Citations are publications that use Tocris products.

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for β-Alanine

Protocols

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