Discontinued Product

AzP3S (Cat. No. 7975) has been withdrawn from sale for commercial reasons.
Description: Reagent for modifying RNA via 2'-OH sulfonylation; for SHAPE MaP experiments
Chemical Name: 5-((1H-1,2,4-Triazol-1-yl)sulfonyl)-2-(3-(2-(2-azidoethoxy)ethoxy)prop-1-yn-1-yl)pyridine
Purity: ≥95% (HPLC)
Literature (2)

Biological Activity for AzP3S

AzP3S is a pyridine sulfonyl triazole for modifying RNA via RNA 2'-OH sulfonylation. AzP3S can be used for RNA SHAPE-MaP experiments in cell lines and bacteria. Allows fluorescent labeling of RNA using Cu-free click chemistry. Stable in aqueous media and in storage at room temperature, can be purified with silica gel chromatography.

Technical Data for AzP3S

M. Wt 377.38
Formula C14H15N7O4S
Storage Store at -20°C
Purity ≥95% (HPLC)
Smiles O=S(C1=CC=C(N=C1)C#CCOCCOCCN=[N+]=[N-])(N2C=NC=N2)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for AzP3S

References are publications that support the biological activity of the product.

Chatterjee et al (2023) Sulfonylation of RNA 2'-OH groups. ACS Cent.Sci 9 531 PMID: 36968531

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Literature in this Area

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