Home / Pharmacology / Enzymes / Kinases / PERK / Azoramide

Azoramide

Cat. No. 5796 Submit a Review Datasheet / COA / SDS

Discontinued Product

5796 has been discontinued.

View all PERK products.
Description: Unfolded protein response (UPR) modulator
Chemical Name: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)
Biological Activity Technical Data Datasheets References

Biological Activity for Azoramide

Modulator of unfolded protein response (UPR). Protects cells from ER stress by improving ER protein folding and activating ER chaperone capacity. Also improves ER calcium retention. Improves liver ER function, glucose homeostasis and glucose-stimulated insulin secretion in mouse obesity models. Orally bioavailable.

Technical Data for Azoramide

M. Wt 308.83
Formula C15H17ClN2OS
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 932986-18-0
PubChem ID 7518316
InChI Key VYBFWKKCWTXCQX-UHFFFAOYSA-N
Smiles ClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Azoramide

References are publications that support the biological activity of the product.

Fu et al (2015) Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity. Sci.Transl.Med. 7 292ra98 PMID: 26084805

View Related Products by Target

Keywords: Azoramide, Azoramide supplier, unfolded, protein, response, UPR, endoplasmic, reticulum, stress, ER, antidiabetic, orally, bioavailable, folding, modulators, PERK, Other, stress/UPR, 5796, Tocris Bioscience

Citations for Azoramide

Citations are publications that use Tocris products.

Currently there are no citations for Azoramide.

Reviews for Azoramide

There are currently no reviews for this product. Be the first to review Azoramide and earn rewards!

Have you used Azoramide?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cell Cycle and DNA Damage Research Product Guide

Cell Cycle and DNA Damage Research Product Guide

This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:

  • Cell Cycle and Mitosis
  • DNA Damage Repair
  • Targeted Protein Degradation
  • Ubiquitin Proteasome Pathway
  • Chemotherapy Targets