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Tocriscreen Kinase Inhibitor 3.0 New
Biological Activity for Tocriscreen Kinase Inhibitor 3.0
Tocriscreen Kinase Inhibitor 3.0 library is a collection of 210 kinase inhibitors supplied pre-dissolved in DMSO (100 μL 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting >60 different kinases, including extensive coverage of well-established targets such as VEFGR and AKT, as well as novel targets such as Haspin and DYRK. The Tocriscreen Kinase Inhibitor 3.0 library is suitable for high-throughput screening (HTS), cell based high-content screening (HCS) and chemical biology applications.
If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.
Key Format and Product Details for Tocriscreen Kinase Inhibitor 3.0
- 96-well racks with TrakMate tubes & SepraSeal caps
- Pre-dissolved in DMSO
- Compounds arranged 80 per rack with 3 racks per library
- Many compounds are exclusive to Tocris
- Full chemical and biological data available
- Exceptional purity
Major IUPHAR kinase subfamilies covered by Tocriscreen Kinase Inhibitor 3.0 Library. TK (tyrosine kinase, 29%); CMGC (includes CDK, MAPK, GSK3 and CLK families, 19%); TKL (tyrosine kinase-like, 16%); AGC (includes PKA, PKG and PKC families, 11%); Atypical (7%); CAMK, (calcium/calmodulin-dependent protein kinases, 4%) and Other Kinases (includes CAMKK, CK1 and STE, 14%).
Request Compound List
To request a list of the compounds available in the Tocriscreen Kinase Inhibitor 3.0 please click the request tile below. Compound lists can be provided in Excel or SD format.
Technical Data for Tocriscreen Kinase Inhibitor 3.0
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Tocriscreen Kinase Inhibitor 3.0
References for Tocriscreen Kinase Inhibitor 3.0
References are publications that support the biological activity of the product.
If you know of a relevant reference for Tocriscreen Kinase Inhibitor 3.0, please let us know.
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12 Citations for Tocriscreen Kinase Inhibitor 3.0
Citations are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor 3.0 include:
Gull et al (2022) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc. PMID: 36180216
Carlson et al (2022) Discovery and characterization of multiple classes of human CatSper blockers. Chem Med Chem 17 e202000499 PMID: 35644882
Lee et al (2021) A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance. Int J Dev Biol 65 523 PMID: 34549798
Hewage et al (2020) Chemical manipulation of abscisic acid signaling: a new approach to abiotic and biotic stress management in agriculture. Adv.Sci. 7 2001265 PMID: 32999840
Wang et al (2019) EGFR-Aurka signaling rescues polarity and regeneration defects in dystrophin-deficient muscle stem cells by increasing asymmetric divisions. Cell Stem Cell 24 419 PMID: 30713094
Moret et al (2019) Cheminformatics tools for analyzing and designing optimized small-molecule collections and libraries. Cell Chem Biol 26 765 PMID: 30956147
Chaudhari et al (2019) Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells. Stem Cells 37 306 PMID: 30471152
Yang et al (2019) NTRK1 is a positive regulator of YAP oncogenic function. Oncogene 38 2778 PMID: 30542115
Azad et al (2018) A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat Commun 9 1061 PMID: 29535383
Moeschler et al (2018) 1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features. Viruses 10 E306 PMID: 29874821
Tomilov et al (2018) Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition. Pharmacol Res 137 89 PMID: 30290222
Markussen et al (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci.Rep. 8 3469 PMID: 29472592
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.