Amyloid β-Peptide (10-20) (human)

Discontinued Product

Amyloid β-Peptide (10-20) (human) (Cat. No. 1892) has been withdrawn from sale for commercial reasons.
Cat.No. 1892 - Amyloid b-peptide (10-20) (human) | Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe | CAS No. 152286-31-2
Description: Amyloid β-peptide; substrate for MMP-2
Alternative Names: β-AP (10-20)
Datasheet
Citations
Reviews
Literature

Biological Activity

Soluble amyloid β-peptide fragment that is a substrate for gelatinase A/type IV collagenase/MMP-2 and APP secretase; cleaved between Lys16 and Leu17.

Technical Data

M. Wt 1446.67
Formula C71H99N17O16
Sequence YEVHHQKLVFF
Storage Desiccate at -20°C
CAS Number 152286-31-2
Smiles [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

References

References are publications that support the biological activity of the product.

Miyazaki et al (1993) A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor. Nature 362 839 PMID: 8479521

Roher et al (1994) Proteolysis of Aβ peptide from Alzheimer disease brain by gelatinase A. Biochem.Biophys.Res.Commun. 205 1755 PMID: 7811262

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Citations for Amyloid β-Peptide (10-20) (human)

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