Alfacalcidol

Pricing Availability Delivery Time Qty
Cat.No. 4159 - Alfacalcidol | C27H44O2 | CAS No. 41294-56-8
Description: Prodrug of vitamin D3 (Cat. No. 4156)
Alternative Names: 1-Hydroxycholecalciferol
Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol
Purity: ≥97% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Metabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.

Technical Data

M. Wt 400.64
Formula C27H44O2
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 41294-56-8
PubChem ID 5282181
InChI Key OFHCOWSQAMBJIW-AVJTYSNKSA-N
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](CCCC(C)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.06 100
ethanol 40.06 100

Preparing Stock Solutions

The following data is based on the product molecular weight 400.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.5 mL 12.48 mL 24.96 mL
5 mM 0.5 mL 2.5 mL 4.99 mL
10 mM 0.25 mL 1.25 mL 2.5 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770 PMID:


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View Related Products by Target

Keywords: VDR activators vitamin D3 analogue analog receptors 1-Hydroxycholecalciferol Vitamin D Receptors

Citations for Alfacalcidol

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Literature in this Area

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Pathways for Alfacalcidol

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