Discontinued Product

Alfacalcidol (Cat. No. 4159) has been withdrawn from sale for commercial reasons.
Cat.No. 4159 - Alfacalcidol | C27H44O2 | CAS No. 41294-56-8
Description: Prodrug of vitamin D3 (Cat. No. 4156)
Alternative Names: 1-Hydroxycholecalciferol
Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol
Purity: ≥97% (HPLC)
Literature (2)

Biological Activity for Alfacalcidol

Alfacalcidol is a metabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.

Technical Data for Alfacalcidol

M. Wt 400.64
Formula C27H44O2
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 41294-56-8
PubChem ID 5282181
Smiles C[C@@](CCC2)3[C@](CC[C@@]([H])3[C@@H](CCCC(C)C)C)([H])/C2=C/C=C(C[C@@H](O)C[C@@H]1O)\C1=C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Alfacalcidol

References are publications that support the biological activity of the product.

Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770

View Related Products by Target

Keywords: Alfacalcidol, Alfacalcidol supplier, VDR, activators, vitamin, D3, analogue, analog, receptors, 1-Hydroxycholecalciferol, Vitamin, D, Receptors, 4159, Tocris Bioscience

Citations for Alfacalcidol

Citations are publications that use Tocris products.

Currently there are no citations for Alfacalcidol.

Reviews for Alfacalcidol

There are currently no reviews for this product. Be the first to review Alfacalcidol and earn rewards!

Have you used Alfacalcidol?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Nuclear Receptors

Nuclear Receptors Product Listing

A collection of over 150 products for key nuclear receptors, the listing includes research tools for the study of:

  • Androgen Receptors
  • Estrogen Receptors
  • Retinoic Acid Receptors
  • Retinoid X Receptors
  • Vitamin D Receptors