Agmatine sulfate

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Cat.No. 0842 - Agmatine sulfate | C5H14N4.H2SO4 | CAS No. 2482-00-0
Description: α2 ligand. Also imidazoline ligand
Chemical Name: (4-Aminobutyl)guanidine sulfate
Datasheet
Citations (1)
Literature

Biological Activity

Arginine metabolite that is synthesized within bovine brain and exhibits clonidine-displacing substance (CDS) activity. Putative endogenous ligand for the imidazoline binding site.

Technical Data

M. Wt 228.27
Formula C5H14N4.H2SO4
Storage Store at RT
CAS Number 2482-00-0
PubChem ID 199
InChI Key QYPPJABKJHAVHS-UHFFFAOYSA-N
Smiles OS(O)(=O)=O.NCCCCNC(N)=N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 228.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.38 mL 21.9 mL 43.81 mL
5 mM 0.88 mL 4.38 mL 8.76 mL
10 mM 0.44 mL 2.19 mL 4.38 mL
50 mM 0.09 mL 0.44 mL 0.88 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Li et al (1994) Agmatine: an endogenous clonidine-displacing substance in the brain. 263 966 PMID: 7906055

Piletz et al (1995) Comparison of the properties of agmatine and endogenous clonidine-displacing substance at imidazoline and alpha-2-adrenergic receptors. J.Pharmacol.Exp.Ther. 272 581 PMID: 7853171

Reis and Regunathan (2000) Is agmatine a novel neurotransmitter in brain? TiPs 21 187 PMID: 10785653

Merck Index 12 186 PMID:


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1 Citation for Agmatine sulfate

Citations are publications that use Tocris products. Selected citations for Agmatine sulfate include:

Kim et al (2011) Icilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation. Brain Res 1384 110 PMID: 21315691


Do you know of a great paper that uses Agmatine sulfate from Tocris? If so please let us know.

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