ACPT-I

Discontinued Product

ACPT-I (Cat. No. 1111) has been withdrawn from sale for commercial reasons.
Description: Group III mGlu agonist
Chemical Name: (1S,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid
Datasheet
Citations (1)
Reviews
Literature (3)

Biological Activity for ACPT-I

ACPT-I is a agonist for group III mGlu receptors (EC50 values are 7.2 and 8.2 μM for mGlu4a and mGlu8 respectively). Anticonvulsant in mice.

Licensing Information

Sold with the permission of the CNRS

Technical Data for ACPT-I

M. Wt 217.18
Formula C8H11NO6
Storage Desiccate at -20°C
CAS Number 194918-76-8
PubChem ID 4302960
InChI Key JARNORYOPMINDY-UHFFFAOYSA-N
Smiles N[C@]1([C@](O)=O)C[C@@H]([C@](O)=O)[C@@H]([C@@](O)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for ACPT-I

Certificate of Analysis / Product Datasheet
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View all Glutamate (Metabotropic) Group III Receptor Agonists

Keywords: ACPT-I, ACPT-I supplier, Group, III, agonists, Receptors, mGlu4, mGlu6, mGlu7, mGlu8, mGluR4, mGluR6, mGluR7, mGluR8, Glutamate, Metabotropic, (Metabotropic), 1111, Tocris Bioscience

1 Citation for ACPT-I

Citations are publications that use Tocris products. Selected citations for ACPT-I include:

Domin et al (2014) Group III mGlu receptor agonist, ACPT-I, exerts potential neuroprotective effects in vitro and in vivo. Proc Natl Acad Sci U S A 26 99 PMID: 24402869


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.