ACPA (in Tocrisolve™ 100)
Potent and selective CB1 agonist (Ki = 2.2 nM), in water-soluble emulsion (for details see TocrisolveTM 100, Cat. No. 1684). Displays 325-fold selectivity over CB2 receptors and is active in vivo. ACPA also available (pure oil dissolved in ethanol, Cat. No. 1318).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 343.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.91 mL||14.55 mL||29.11 mL|
|5 mM||0.58 mL||2.91 mL||5.82 mL|
|10 mM||0.29 mL||1.46 mL||2.91 mL|
|50 mM||0.06 mL||0.29 mL||0.58 mL|
References are publications that support the products' biological activity.
Hillard et al (1999) Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J.Pharmacol.Exp.Ther. 289 1427 PMID: 10336536
Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635 PMID: 10469884
If you know of a relevant reference for ACPA (in Tocrisolve™ 100), please let us know.
View Related Products by Product Action
Keywords: ACPA (in Tocrisolve 100), supplier, Potent, selective, CB1, agonists, water-soluble, emulsion, cannabinoids, Receptors, cb1r, Arachidonylcyclopropylamide, CB1, Receptors, CB1, Receptors, Tocris Bioscience
1 Citation for ACPA (in Tocrisolve™ 100)
Citations are publications that use Tocris products. Selected citations for ACPA (in Tocrisolve™ 100) include:
Niu et al (2012) Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats. Sleep 153 2283 PMID: 22940464
Do you know of a great paper that uses ACPA (in Tocrisolve™ 100) from Tocris? If so please let us know.
ACPA (in Tocrisolve 100) Reviews
Average Rating:(Based on 0 Reviews)
Literature in this Area
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.