ACPA (in Tocrisolve™ 100)

Pricing Availability Delivery Time Qty
Cat.No. 1781 - ACPA (in Tocrisolve 100) | C23H37NO | CAS No. 229021-64-1
Description: Potent, selective CB1 agonist (in water-soluble emulsion)
Alternative Names: Arachidonylcyclopropylamide
Chemical Name: N-(Cyclopropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Datasheet
Citations (1)
Literature

Biological Activity

Potent and selective CB1 agonist (Ki = 2.2 nM), in water-soluble emulsion (for details see TocrisolveTM 100, Cat. No. 1684). Displays 325-fold selectivity over CB2 receptors and is active in vivo. ACPA also available (pure oil dissolved in ethanol, Cat. No. 1318).

Technical Data

M. Wt 343.55
Formula C23H37NO
Storage Store at +4°C
CAS Number 229021-64-1
PubChem ID 5311007
InChI Key GLGAUBPACOBAMV-DOFZRALJSA-N
Smiles O=C(NC1CC1)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 343.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.91 mL 14.55 mL 29.11 mL
5 mM 0.58 mL 2.91 mL 5.82 mL
10 mM 0.29 mL 1.46 mL 2.91 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Hillard et al (1999) Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J.Pharmacol.Exp.Ther. 289 1427 PMID: 10336536

Pertwee (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635 PMID: 10469884

Patel et al (2001) Cannabinoid CB1 receptor agonists produce cerebellar dysfunction in mice. 2001 Symposium on the Cannabinoids, International PMID:


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Keywords: ACPA (in Tocrisolve 100), supplier, Potent, selective, CB1, agonists, water-soluble, emulsion, cannabinoids, Receptors, cb1r, Arachidonylcyclopropylamide, CB1, Receptors, CB1, Receptors, Tocris Bioscience

1 Citation for ACPA (in Tocrisolve™ 100)

Citations are publications that use Tocris products. Selected citations for ACPA (in Tocrisolve™ 100) include:

Niu et al (2012) Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats. Sleep 153 2283 PMID: 22940464


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