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Discontinued ProductAcetyl Pepstatin (Cat. No. 5852) has been withdrawn from sale for commercial reasons.
Biological Activity for Acetyl Pepstatin
Acetyl Pepstatin is a high affinity aspartic protease inhibitor. Inhibits HIV-1 protease (Ki = 20 nM at pH 4.7) and HIV-2 protease (Ki = 5 nM at pH 4.7). Antiviral.
Technical Data for Acetyl Pepstatin
(Modifications: Val-1 = N-terminal Ac, Val-2 = Val-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl, Ala-3 = Ala-(3S,4S)4-amino-3-hydroxy-6-methylheptanoic-acid)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Acetyl Pepstatin
References for Acetyl Pepstatin
References are publications that support the biological activity of the product.
Matúz et al (2012) Inhibition of XMRV and HIV-1 proteases by pepstatin A and acetyl-pepstatin. FEBS J. 279 3276 PMID: 22804908
Richards et al (1989) Effective blocking of HIV-1 proteinase activity by characteristic inhibitors of aspartic proteinases. FEBS Lett. 247 113 PMID: 2651157
Richards et al (1989) Inhibition of the aspartic proteinase from HIV-2. FEBS Lett. 253 214 PMID: 2668032
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Citations for Acetyl Pepstatin
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Currently there are no citations for Acetyl Pepstatin.
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Literature in this Area
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