7-Hydroxy-DPAT hydrobromide

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Cat.No. 0706 - 7-Hydroxy-DPAT hydrobromide | C16H25NO.HBr | CAS No. 76135-30-3
Description: Dopamine agonist (D3 ≥ D2 < > D4)
Chemical Name: (±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (5)

Biological Activity

D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively).

8-Hydroxy Isomer also available.

Compound Libraries

7-Hydroxy-DPAT hydrobromide is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 328.28
Formula C16H25NO.HBr
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 76135-30-3
PubChem ID 11957566
InChI Key ODNDMTWHRYECKX-UHFFFAOYSA-N
Smiles Br.CCCN(CCC)C1CCC2=CC=C(O)C=C2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.83 100

Preparing Stock Solutions

The following data is based on the product molecular weight 328.28. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.05 mL 15.23 mL 30.46 mL
5 mM 0.61 mL 3.05 mL 6.09 mL
10 mM 0.3 mL 1.52 mL 3.05 mL
50 mM 0.06 mL 0.3 mL 0.61 mL

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Dilution Calculator

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References

References are publications that support the biological activity of the product.

Daly and Waddington (1993) Behavioural effects of the D3 DA receptor agonist 7-OH-DPAT in relation to other D2-like agonists. Neuropharmacology 32 509 PMID: 8321432

Levesque (1996) Aminotetralin drugs and D3 receptor fuctions. Biochem.Pharmacol. 52 511 PMID: 8759022

Levesque et al (1992) Identification, characterization, and localization of the DA D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc.Natl.Acad.Sci.U.S.A. 89 8155 PMID: 1518841

Seeman and Van Tol (1994) DA receptor pharmacology. TiPS 15 264 PMID: 7940991


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Keywords: 7-Hydroxy-DPAT hydrobromide, 7-Hydroxy-DPAT hydrobromide supplier, Dopamine, agonists, D3, Receptors, dopaminergic, 0706, Tocris Bioscience

Citations for 7-Hydroxy-DPAT hydrobromide

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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