Discontinued Product6-Nitroindazole (Cat. No. 0710) has been withdrawn from sale for commercial reasons.
nNOS inhibitor. Less potent antinociceptive than the 7-nitro analogue (0602), but is equally potent in relaxing smooth muscle independently of its inhibition of NO synthase.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Medhurst et al (1994) NO synthase inhibitors 7- and 6-nitroindazole relax smooth muscle in vitro. Eur.J.Pharmacol. 256 R5 PMID: 7517888
Moore et al (1993) Characterisation of the novel NO synthase inhibitor 7-nitroindazole and related indazoles: antinociceptive and cardiovascular effects. Br.J.Pharmacol. 110 219 PMID: 7693278
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Keywords: 6-Nitroindazole, 6-Nitroindazole supplier, nNOS, 0710, Tocris Bioscience
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Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.