5-OMe-UDP trisodium salt

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Cat.No. 4376 - 5-OMe-UDP trisodium salt | C10H13N2Na3O13P2
Description: Potent P2Y6 agonist
Chemical Name: 5-Methoxyuridine 5'-diphosphate trisodium salt
Purity: ≥98% (HPLC)
Citations (1)
Literature (5)

Biological Activity for 5-OMe-UDP trisodium salt

5-OMe-UDP trisodium salt is a potent P2Y6 agonist (EC50 = 0.08 μM). Displays greater potency at P2Y6 than UDP (Cat.No. 3111) (EC50 = 0.14 μM).

Technical Data for 5-OMe-UDP trisodium salt

M. Wt 500.13
Formula C10H13N2Na3O13P2
Storage Store at -20°C
Purity ≥98% (HPLC)
PubChem ID 90488936
Smiles [Na+].[Na+].[Na+].COC1CN(C)C(O)N([C@@H]2O[C@H](COP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]2O)C1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 5-OMe-UDP trisodium salt

Solubility Soluble in water (supplied pre-dissolved at a concentration of 10mM)

Product Datasheets for 5-OMe-UDP trisodium salt

References for 5-OMe-UDP trisodium salt

References are publications that support the biological activity of the product.

Ginsburg-Shmuel et al (2010) 5-OMe-UDP is a potent and selective P2Y6-receptor agonist. J.Med.Chem. 53 1673 PMID: 20095577

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Keywords: 5-OMe-UDP trisodium salt, 5-OMe-UDP trisodium salt supplier, purinergic, receptors, purinoceptor, p2y6, agonists, purine, receptor, agonist, 1207530-98-0, Purinergic, P2Y, Receptors, 4376, Tocris Bioscience

1 Citation for 5-OMe-UDP trisodium salt

Citations are publications that use Tocris products. Selected citations for 5-OMe-UDP trisodium salt include:

Hansen et al (2013) The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction. Psychopharmacology (Berl) 8 e81491 PMID: 24278446

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Literature in this Area

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