5-OMe-UDP trisodium salt
Biological Activity
Potent P2Y6 agonist (EC50 = 0.08 μM). Displays greater potency at P2Y6 than UDP (Cat.No. 3111) (EC50 = 0.14 μM).
Technical Data
| M. Wt | 500.13 |
| Formula | C10H13N2Na3O13P2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1207530-98-0 |
| PubChem ID | 90488936 |
| InChI Key | IGMOCSFADHRLMQ-QAUZTDKFSA-K |
| Smiles | [Na+].[Na+].[Na+].COC1CN(C)C(O)N([C@@H]2O[C@H](COP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]2O)C1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Preparing Stock Solutions
The following data is based on the product molecular weight 500.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2 mL | 10 mL | 19.99 mL |
| 5 mM | 0.4 mL | 2 mL | 4 mL |
| 10 mM | 0.2 mL | 1 mL | 2 mL |
| 50 mM | 0.04 mL | 0.2 mL | 0.4 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Ginsburg-Shmuel et al (2010) 5-OMe-UDP is a potent and selective P2Y6-receptor agonist. J.Med.Chem. 53 1673 PMID: 20095577
If you know of a relevant reference for 5-OMe-UDP trisodium salt, please let us know.
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Keywords: 5-OMe-UDP trisodium salt, supplier, purinergic, receptors, purinoceptor, p2y6, agonists, purine, receptor, agonist, Purinergic, P2Y, Receptors, Tocris Bioscience
1 Citation for 5-OMe-UDP trisodium salt
Citations are publications that use Tocris products. Selected citations for 5-OMe-UDP trisodium salt include:
Hansen et al (2013) The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction. Psychopharmacology (Berl) 8 e81491 PMID: 24278446
Do you know of a great paper that uses 5-OMe-UDP trisodium salt from Tocris? If so please let us know.
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