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Submit Review5-OMe-UDP trisodium salt
Description: Potent P2Y6 agonist
Chemical Name: 5-Methoxyuridine 5'-diphosphate trisodium salt
Purity: ≥98% (HPLC)
Biological Activity
Potent P2Y6 agonist (EC50 = 0.08 μM). Displays greater potency at P2Y6 than UDP (Cat.No. 3111) (EC50 = 0.14 μM).
Technical Data
| M. Wt | 500.13 |
| Formula | C10H13N2Na3O13P2 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1207530-98-0 |
| PubChem ID | 90488936 |
| InChI Key | IGMOCSFADHRLMQ-QAUZTDKFSA-K |
| Smiles | [Na+].[Na+].[Na+].COC1CN(C)C(O)N([C@@H]2O[C@H](COP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]2O)C1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Product Datasheets
References
References are publications that support the biological activity of the product.
Ginsburg-Shmuel et al (2010) 5-OMe-UDP is a potent and selective P2Y6-receptor agonist. J.Med.Chem. 53 1673 PMID: 20095577
If you know of a relevant reference for 5-OMe-UDP trisodium salt, please let us know.
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Keywords: 5-OMe-UDP trisodium salt, 5-OMe-UDP trisodium salt supplier, purinergic, receptors, purinoceptor, p2y6, agonists, purine, receptor, agonist, Purinergic, P2Y, Receptors, 4376, Tocris Bioscience
1 Citation for 5-OMe-UDP trisodium salt
Citations are publications that use Tocris products. Selected citations for 5-OMe-UDP trisodium salt include:
Hansen et al (2013) The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction. Psychopharmacology (Berl) 8 e81491 PMID: 24278446
Do you know of a great paper that uses 5-OMe-UDP trisodium salt from Tocris? Please let us know.
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