UDP disodium salt

Pricing Availability Delivery Time Qty
Cat.No. 3111 - UDP disodium salt | C9H12N2Na2O12P2 | CAS No. 27821-45-0
Description: Endogenous ligand; competitive antagonist at P2Y14 receptors
Chemical Name: Uridine-5'-diphosphate disodium salt
Purity: ≥97% (HPLC)
Datasheet
Citations (2)
Literature

Biological Activity

Endogenous P2Y receptor agonist which preferentially activates P2Y6. Shown to be a competitive antagonist at P2Y14 receptors.

Technical Data

M. Wt 448.12
Formula C9H12N2Na2O12P2
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 27821-45-0
PubChem ID 11957711
InChI Key ZQKVPFKBNNAXCE-WFIJOQBCSA-L
Smiles [Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N1C=CC(=O)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 44.81 100

Preparing Stock Solutions

The following data is based on the product molecular weight 448.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.23 mL 11.16 mL 22.32 mL
5 mM 0.45 mL 2.23 mL 4.46 mL
10 mM 0.22 mL 1.12 mL 2.23 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet

References

References are publications that support the products' biological activity.

Ralevic and Burnstock (1998) Receptors for purines and pyrimidines. Pharmacol.Rev. 50 413 PMID: 9755289

Fricks et al (2008) UDP is a competitive antagonist at the human P2Y14 receptor. J.Pharmacol.Exp.Ther. 325 588 PMID: 18252808


If you know of a relevant reference for UDP disodium salt, please let us know.

View Related Products by Target

Keywords: UDP disodium salt, supplier, Endogenous, ligands, competitive, antagonists, P2Y14, receptors, Purinergic, purinoceptors, Purinergic, P2Y, Receptors, Purinergic, P2Y, Receptors, Tocris Bioscience

2 Citations for UDP disodium salt

Citations are publications that use Tocris products. Selected citations for UDP disodium salt include:

Obba et al (2015) The PRKAA1/AMPK╬▒1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML. Alcohol Clin Exp Res 11 1114 PMID: 26029847

Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050 PMID: 24048730


Do you know of a great paper that uses UDP disodium salt from Tocris? If so please let us know.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

Cardiovascular

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure
GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
P2X and P2Y Receptors

P2X and P2Y Receptors Scientific Review

Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.

Cardiovascular

Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.

Pathways for UDP disodium salt

Protocols

TODO: Add Protocols