UDP disodium salt

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Cat.No. 3111 - UDP disodium salt | C9H12N2Na2O12P2 | CAS No. 27821-45-0
Description: Endogenous ligand; competitive antagonist at P2Y14 receptors
Chemical Name: Uridine-5'-diphosphate disodium salt
Purity: ≥97% (HPLC)
Datasheet
Citations (2)
Reviews (1)
Literature (5)

Biological Activity

Endogenous P2Y receptor agonist which preferentially activates P2Y6. Shown to be a competitive antagonist at P2Y14 receptors.

Technical Data

M. Wt 448.12
Formula C9H12N2Na2O12P2
Storage Store at -20°C
Purity ≥97% (HPLC)
CAS Number 27821-45-0
PubChem ID 11957711
InChI Key ZQKVPFKBNNAXCE-WFIJOQBCSA-L
Smiles [Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N1C=CC(=O)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 44.81 100

Preparing Stock Solutions

The following data is based on the product molecular weight 448.12. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.23 mL 11.16 mL 22.32 mL
5 mM 0.45 mL 2.23 mL 4.46 mL
10 mM 0.22 mL 1.12 mL 2.23 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Ralevic and Burnstock (1998) Receptors for purines and pyrimidines. Pharmacol.Rev. 50 413 PMID: 9755289

Fricks et al (2008) UDP is a competitive antagonist at the human P2Y14 receptor. J.Pharmacol.Exp.Ther. 325 588 PMID: 18252808


If you know of a relevant reference for UDP disodium salt, please let us know.

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Keywords: UDP disodium salt, UDP disodium salt supplier, Endogenous, ligands, competitive, antagonists, P2Y14, receptors, Purinergic, purinoceptors, P2Y, Receptors, 3111, Tocris Bioscience

2 Citations for UDP disodium salt

Citations are publications that use Tocris products. Selected citations for UDP disodium salt include:

Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050 PMID: 24048730

Obba et al (2015) The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML. Alcohol Clin Exp Res 11 1114 PMID: 26029847


Do you know of a great paper that uses UDP disodium salt from Tocris? Please let us know.

Reviews for UDP disodium salt

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P2Y6 activation (P2Y6).
By Anonymous on 10/22/2018
Assay Type: Ex Vivo
Species: Mouse

Applied directly on a tissue slice to activate P2Y receptors (P2Y6 mostly). Elicited expected cellular response.


Literature in this Area

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