Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative is a precursor to the highly potent and selective ligand for the α4β2 nicotinic receptor, 5-Iodo-A-85380 (Cat. No.1518). Suitable for radioiodination.
M. Wt | 427.11 |
Formula | C17H28N2O3Sn |
Storage | Desiccate at -20°C |
Purity | ≥98% (HPLC) |
CAS Number | 213766-21-3 |
PubChem ID | 10574471 |
InChI Key | HHNYNAVVSDTMQD-HZAYLZKLSA-N |
Smiles | O=C(N1[C@H](COC2=CC([Sn](C)(C)C)=CN=C2)CC1)OC(C)(C)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Koren et al (1998) 2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling. J.Med.Chem. 41 3690 PMID: 9733494
Mukhin et al (2000) 5-Iodo-A-85380, an α4β2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol.Pharmacol. 57 642 PMID: 10692507
Keywords: 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative, 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative supplier, Precursor, α4β2, a4b2, Nicotinic, Receptors, Acetylcholine, nAChR, Non-Selective, Subtypes, Other, 5-Iodo-A-853805-trimethylstannyl, N-BOC, derivative, (Other, Subtypes), (a4b2), 1527, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative.
There are currently no reviews for this product. Be the first to review 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.