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Submit ReviewWeak GABAB antagonist, also GABAA agonist.
M. Wt | 153.61 |
Storage | Desiccate at -20°C |
CAS Number | 660-88-8 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Falch et al (1986) Comparative stereostructure-activity studies of GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J.Neurochem. 47 898 PMID: 3016189
Keywords: 5-Aminopentanoic acid hydrochloride, 5-Aminopentanoic acid hydrochloride supplier, d-Aminovaleric, acid, GABAA, Receptors, GABAB, 0263, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.