Discontinued Product

4Cl-3,5-DHPG (Cat. No. 1013) has been withdrawn from sale for commercial reasons.
Description: Group III mGlu agonist
Chemical Name: (RS)-4-Chloro-3,5-dihydroxyphenylglycine
Literature (4)

Biological Activity for 4Cl-3,5-DHPG

Metabotropic glutamate receptor agonist, with some selectivity for the mGlu6 subtype but also active at mGlu1, as determined at recombinant receptors expressed in CHO cells.

Technical Data for 4Cl-3,5-DHPG

M. Wt 217.61
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for 4Cl-3,5-DHPG

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for 4Cl-3,5-DHPG

References are publications that support the biological activity of the product.

Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493 PMID: 8730745

Thoreson et al (1997) Two phenylglycine derivatives antagonize responses to L-AP4 in ON bipolar cells of the amphibian retina. Neuropharmaoclogy 36 13 PMID: 9144637

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Keywords: 4Cl-3,5-DHPG, 4Cl-3,5-DHPG supplier, Glutamate, (Metabotropic), Group, III, Receptors, 1013, Tocris Bioscience

Citations for 4Cl-3,5-DHPG

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Currently there are no citations for 4Cl-3,5-DHPG.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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