Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
4-Chlorophenylguanidine hydrochloride is a potent and specific inhibitor of urokinase. Also a positive allosteric modulator at acid sensing ion channel 3 (ASIC3), which increases its pH sensitivity.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 206.07. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.85 mL||24.26 mL||48.53 mL|
|5 mM||0.97 mL||4.85 mL||9.71 mL|
|10 mM||0.49 mL||2.43 mL||4.85 mL|
|50 mM||0.1 mL||0.49 mL||0.97 mL|
References are publications that support the biological activity of the product.
Yang et al (1990) Selective inhibition of urok. by substituted phenylguanidines: quantitative structure-activity relationship analyses. J.Med.Chem. 33 2956 PMID: 2231595
Agharkar & Gonzales (2017) 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J.Pharmacol.Sci. 133 184 PMID: 28259560
If you know of a relevant reference for 4-Chlorophenylguanidine hydrochloride, please let us know.
Keywords: 4-Chlorophenylguanidine hydrochloride, 4-Chlorophenylguanidine hydrochloride supplier, Urokinase, inhibitors, inhibits, Proteases, Proteinases, upa, PAM, ASIC, 0442, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for 4-Chlorophenylguanidine hydrochloride include:
Agharkar & Gonzales 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J.Pharmacol.Sci. 133 184 PMID: 28259560
Do you know of a great paper that uses 4-Chlorophenylguanidine hydrochloride from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review 4-Chlorophenylguanidine hydrochloride and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.