3-CPMT

Discontinued Product

3-CPMT (Cat. No. 0917) has been withdrawn from sale for commercial reasons.
Cat.No. 0917 - 3-CPMT | C21H24ClNO.HCl | CAS No. 14008-79-8
Description: Dopamine uptake inhibitor
Chemical Name: 3α-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (4)

Biological Activity

This cocaine analog binds with high affinity to the dopamine transporter (Ki = 30 nM) and blocks re-uptake of dopamine. However, it is a weak psychomotor stimulant and does not substitute for cocaine in addicted rats.

Technical Data

M. Wt 378.34
Formula C21H24ClNO.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 14008-79-8
PubChem ID 203135
InChI Key FXKCQWIUITUJFU-UHFFFAOYSA-N
Smiles Cl.CN1C2CCC1CC(C2)OC(C1=CC=CC=C1)C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

Newman et al (1994) Novel 3α-(diphenylmethoxy)tropane analogs: potent DA uptake inhibitors without cocaine-like behavioural profiles. J.Med.Chem. 37 2258 PMID: 8057273

Newman et al (1995) Novel 4'-substituted and 4'4"-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective DA uptake inhibitors. J.Med.Chem. 38 3933 PMID: 7562926

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Keywords: 3-CPMT, 3-CPMT supplier, Dopamine, reuptake, inhibitors, inhibits, DAT, Transporters, Monoamine, Neurotransmitter, 0917, Tocris Bioscience

Citations for 3-CPMT

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Currently there are no citations for 3-CPMT.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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Dopamine Receptors Scientific Review

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