Potent inhibitor of rat cerebellar nitric oxide synthase; more potent than 7-nitroindazole (Cat. No. 0602).
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 242.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.13 mL||20.66 mL||41.32 mL|
|5 mM||0.83 mL||4.13 mL||8.26 mL|
|10 mM||0.41 mL||2.07 mL||4.13 mL|
|50 mM||0.08 mL||0.41 mL||0.83 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Bland-Ward and Moore (1995) 7-Nitroindazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase. Life Sci. 57 PL131 PMID: 7544863
If you know of a relevant reference for 3-Bromo-7-nitroindazole, please let us know.
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Keywords: Selective nNOS inhibitors inhibits Nitric Oxide Signaling Signalling Neuronal NO Synthases nNOS
1 Citation for 3-Bromo-7-nitroindazole
Citations are publications that use Tocris products. Selected citations for 3-Bromo-7-nitroindazole include:
Dai et al (2011) Lactate dilates cochlear capillaries via type V fibrocyte-vessel coupling signaled by nNOS. Am J Physiol Heart Circ Physiol 301 H1248 PMID: 21856924
Do you know of a great paper that uses 3-Bromo-7-nitroindazole from Tocris? If so please let us know.
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