Discontinued ProductUnfortunately 2,3-Butanedione monoxime (Cat. No. 0936) has been withdrawn from sale for commercial reasons.
Inhibits myosin-ATPase and induces Ca2+ release from the sarcoplasmic reticulum. Also an anticonvulsant, able to suppress current induced by GABA, glycine and kainate, possibly by altering the phosphorylation state of sites on their receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 101.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||9.89 mL||49.46 mL||98.91 mL|
|5 mM||1.98 mL||9.89 mL||19.78 mL|
|10 mM||0.99 mL||4.95 mL||9.89 mL|
|50 mM||0.2 mL||0.99 mL||1.98 mL|
References are publications that support the products' biological activity.
Phillips and Altschuld (1996) 2,3-Butanedione 2-monoxime (BDM) induces calcium release from canine cardiac sarcoplasmic reticulum. Biochem.Biophys.Res.Commun. 229 154 PMID: 8954098
Soeno et al (1999) BDM (2,3-butanedione monoxime), an inhibitor of myosin-actin interaction, suppresses myofibrillogenesis in skeletal muscle cells in culture. Cell Tissue Res. 295 307 PMID: 9931377
Wiggins et al (1980) Inotropic actions of diacetyl monoxime in cat ventricular muscle. J.Pharmacol.Exp.Ther. 212 217 PMID: 6243361
View Related Products by Target
View Related Products by Product Action
Keywords: 2,3-Butanedione monoxime, supplier, Myosin, General, Calcium, Signaling, Agents, Myosin, Tocris Bioscience
Citations for 2,3-Butanedione monoxime
Citations are publications that use Tocris products.
Currently there are no citations for 2,3-Butanedione monoxime.
Reviews for 2,3-Butanedione monoxime
There are currently no reviews for this product. Be the first to review 2,3-Butanedione monoxime and earn rewards!
Have you used 2,3-Butanedione monoxime?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.