Discontinued Product

(1S,3S)-ACPD (Cat. No. 0300) has been withdrawn from sale for commercial reasons.
Description: Group II mGlu agonist
Chemical Name: (1S,3S)-1-Aminocyclopentane-1,3-dicarboxylic acid
Literature (5)

Biological Activity for (1S,3S)-ACPD

One of the isomers of (±)-cis-ACPD. Similar action at mGlu receptors to (1S,3R)-ACPD, but more selective for group II. Little or no NMDA receptor agonist activity.

Technical Data for (1S,3S)-ACPD

M. Wt 173.17
Storage Store at RT
CAS Number 111900-31-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for (1S,3S)-ACPD

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for (1S,3S)-ACPD

References are publications that support the biological activity of the product.

Holscher et al (1997) Block of theta-burst-induced long-term potentiation by (1S,3S)-1,3-dicarboxylic acid: further evidence against long-term potentiation as a model for learning. Neuroscience 81 17 PMID: 9300397

Jane et al (1991) Action of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord. Br.J.Pharmacol. 112 809 PMID: 7921606

Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 26 PMID: 7623957

Watkins and Collingridge (1994) Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. TiPS 15 333 PMID: 7992387

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Keywords: (1S,3S)-ACPD, (1S,3S)-ACPD supplier, Glutamate, (Metabotropic), Group, II, Receptors, 0300, Tocris Bioscience

Citations for (1S,3S)-ACPD

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Currently there are no citations for (1S,3S)-ACPD.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Metabotropic Glutamate Receptors Scientific Review

Metabotropic Glutamate Receptors Scientific Review

Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.

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